Validity and reliability of the EQ-5D self-report questionnaire in English-speaking Asian patients with rheumatic diseases in Singapore |
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Authors: | Luo N Chew LH Fong KY Koh DR Ng SC Yoon KH Vasoo S Li SC Thumboo J |
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Institution: | (1) Department of Pharmacy, National University of Singapore, Singapore;(2) School of Health Sciences, Nanyang Polytechnic, Singapore;(3) Department of Medicine, National University of Singapore, Singapore;(4) Department of Medicine, National University Hospital, Singapore |
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Abstract: | Validity and reliability of a Singaporean English EQ-5D self-report questionnaire (EQ-5D) were evaluated among consecutive outpatients with rheumatic diseases attending a tertiary referral hospital in Singapore (a multi-ethnic, urban Asian country). Subjects were interviewed twice within a 2-week period using a standardized questionnaire containing the EQ-5D, Short Form 36 Health Survey (SF-36) and assessing demographic and psychosocial characteristics. To assess validity of the EQ-5D, 13 hypotheses relating responses to EQ-5D dimension/Visual Analogue Scale (EQ-VAS) to SF-36 scores or other variables were examined using the Mann–Whitney test, Kruskal–Wallis test, or Spearman's correlation coefficient. Test–retest reliability was assessed using Cohen's . Sixty-six subjects were studied (osteoarthritis: 9, rheumatoid arthritis: 26, systemic lupus erythematosus: 23, spondyloarthropathy: 8; female: 72.7%; mean age: 44.3 years). Ten of 13 a-priori hypotheses relating EQ-5D responses to external variables were fulfilled, supporting the validity of the EQ-5D. Cohen's for test–retest reliability (n = 52) ranged from 0.29 to 0.61. The Singaporean English EQ-5D appears to be valid in measuring quality of life in Singaporeans with rheumatic diseases; however, its reliability requires further investigation. These data provide a basis for further studies assessing the validity of the EQ-5D in Singapore. |
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Keywords: | Psychometrics Quality of life Reliability of results Rheumatic diseases Singapore |
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