RhD阴性患者血清学表型和不规则抗体筛查结果分析 |
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引用本文: | 王华,张洪为,谭芳,李代渝.RhD阴性患者血清学表型和不规则抗体筛查结果分析[J].现代保健,2011(2):131-133. |
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作者姓名: | 王华 张洪为 谭芳 李代渝 |
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作者单位: | 泸州医学院附属医院,646000 |
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摘 要: | 目的调查和分析医院RbD阴性患者的血清学表现型和不规则抗体筛查的情况。方法采用盐水试管法检测RhD抗原,微柱凝胶法检测Rh—CcEe抗原和不规则抗体。结果共检出RhD阴性176例(占0.37%),其中检出不规则抗体5例(占2.84%)。表现型主要以ccdee和Ccdee为主。结论非紧急情况下,医院应对RhD阴性患者进行血清学表现型和不规则抗体筛查,尽量选择Rh血型相同的血液输注;同时血站应建立一个稳定而具有详细资料的Rh阴性献血者库,以解决血液供需矛盾,及时满足临床用血需求。
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关 键 词: | Rh—D阴性 血清学表现型 不规则抗体 |
Analysis for the situation of the serological phenotype and irregular antibody on the patients with RhD( - ) |
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Institution: | WANG Hua, ZHANG Hong - wei, TAN Fang, LI Dai - yu. The Affiliated Hospital of Luzhou Medical College, Luzhou 646000, China |
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Abstract: | Objective To investigate and analysis the situation of the serological phenotype and irregular antibody on patients with RhD( - ) ( Rh blood group D - negative). Methods Using saline - vitro method to detect RhD antigen, and microcolumn gel test to detect Rh - CcEe antigen and to screen irregular antibodies. Results 176 cases ( accounting for 0. 37% ) with RhD( - ) were detected, including 5 cases of irregular antibodies positive( accounting for 2. 84% ). Most of their phenotype were ccdee and Ccdee. Conclusion At the non - emergency situations, the serological phenotype and irregular antibody should be tested for all patients with RhD( - ) in hospital and the blood was choosed to transfuse to patients with tauto - RhD as far as possible. The database of RhD( - ) donors with detailed information should be established for clinical transfusion in blood bank. |
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Keywords: | RhD( - ) Phenotype Irregular antibody |
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