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| 金属硫蛋白医学研究进展 | |
| 引用本文： | 姚朝阳,朱文文,牛敬媛,郭伟云,邵强,王天云,杨保胜.金属硫蛋白医学研究进展[J].微量元素与健康研究,2007,24(3):53-55,63. |
| 作者姓名： | 姚朝阳 朱文文 牛敬媛 郭伟云 邵强 王天云 杨保胜 |
| 作者单位： | 1. 新乡医学院基础医学院,新乡,453003 2. 河南科技大学食品与生物工程学院,洛阳,471003 3. 新乡医学院生命科技系,新乡,453003 4. 河南师范大学生命科学学院,新乡,453003 |
| 摘 要： | 金属硫蛋白(MT)是一类广泛存在于生物界的金属结合蛋白,因其功能独特,近年来对MT的研究日益受到重视。对MT的分子结构、性质、参与体内微量元素代谢、解除重金属的毒性、清除体内自由基、抗氧化损伤、防止机体衰老、应激能力等生物学功能进行了阐述,并对MT与肿瘤和其它疾病的关系等方面的研究进行了综述,并提出了MT研究中存在的问题及展望。 |
| 关 键 词： | 金属硫蛋白 重金属毒性 生物学功能 肿瘤 |
| 文章编号： | 1005-5320（2007）03-0053-03 |
| 修稿时间： | 2006-11-28 |
The medical research progress of metallothionein |
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| YAO Zhao - yang, ZHU Wen - wen, NIU Jing - yuan, et al.The medical research progress of metallothionein[J].Studies of Trace Elements and Health,2007,24(3):53-55,63. | |
| Authors: | YAO Zhao - yang ZHU Wen - wen NIU Jing - yuan |
| Abstract: | Metallothionein is a kind of metal binding proteins that widely exist in the whole biosphere. The study about MT is valued in all field in recent yeas because its function is unique. This article mainly discusses the molecular structure of MT and its unique feature and its biology functions such as participating in vivo trace dement metabolism and relieveing toxicity of the heavy metal, eliminateing free radical in vivo, anti- oxidized damage, preventing the organism senile function, adaptive capacity , and so on.The relations between MT and tumor and other diseases is also sumed up. And the questions that exist in the investgations is proposed and the future is forecasted. |
| Keywords: | metallothionein toxicity of the heavy metal biology function tumor |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |