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广州市2006年禽流感患者未造成密切接触者传播的调查
引用本文:王玉林,秦鹏哲,刘于飞,吴新伟,柳洋,范建文,湛柳华,郭钜旋,陈小霜,蒋立云,周端华,狄飚,王鸣.广州市2006年禽流感患者未造成密切接触者传播的调查[J].中华流行病学杂志,2006,27(11):953-955.
作者姓名:王玉林  秦鹏哲  刘于飞  吴新伟  柳洋  范建文  湛柳华  郭钜旋  陈小霜  蒋立云  周端华  狄飚  王鸣
作者单位:1. 510080,广州市疾病预防控制中心
2. 荔湾区疾病预防控制中心
3. 越秀区疾病预防控制中心
4. 海珠区疾病预防控制中心
基金项目:(感谢中国疾病预防控制中心传染病预防控制所徐建国研究员,广东省疾病预防控制中心罗会明、何剑峰等专家的指导;感谢中国疾病预防控制中心、广东省疾病预防控制中心及各有关区疾病预防控制中心在本次调查工作中给予的支持和帮助)
摘    要:目的 探讨人感染禽流感的密切接触者传播的可能性。方法 根据卫生部公布的定义和办法,发现和确定密切接触者,开展流行病学调查和医学观察,并检测部分接触者的血清抗体。结果 2006年广州市发生的禽流感患者,在发病前1个月未离开过该地,且无病、死禽的接触史;共发现了56名密切接触者,包括其女友、医务人员、亲属、朋友。经过7天的医学观察,未发现密切接触者被感染的现象。结论 与SARS传播不同,广州市禽流感患者在潜伏期末和发病期间,未发现可能通过飞沫、唾液、黏膜、皮肤伤口直接接触等方式造成人间传播,提示目前禽流感病毒引起人间传播的能力不强。

关 键 词:禽流感  密切接触者  流行病学调查  传播
收稿时间:2006-08-15
修稿时间:2006年8月15日

Study on human case of avian influenza in Guangzhou 2006 without causing human-to-human transmission among close contacts
WANG Yu-lin,QIN Peng-zhe,LIU Yu-fei,WU Xin-wei,LIU Yang,FAN Jian-wen,ZHAN Liu-hu,GUO Ju-xuan,CHEN Xiao-shuang,JIANG Li-yun,ZHOU Duan-hu,DI Biao and WANG Ming.Study on human case of avian influenza in Guangzhou 2006 without causing human-to-human transmission among close contacts[J].Chinese Journal of Epidemiology,2006,27(11):953-955.
Authors:WANG Yu-lin  QIN Peng-zhe  LIU Yu-fei  WU Xin-wei  LIU Yang  FAN Jian-wen  ZHAN Liu-hu  GUO Ju-xuan  CHEN Xiao-shuang  JIANG Li-yun  ZHOU Duan-hu  DI Biao and WANG Ming
Institution:Guangzhou Center for Disease Control and Prevention, Guangzhou 510080, China.
Abstract:Objective To explore the possibility of transmission from a human case of avian influenza to his close contacts.Methods Close contacts of the human case of avian influenza in Guangzhou 2006 were found out according to the definition and methods publicized by the Ministry of Health,People's Republic of China.Epidemiological investigation and medical observation were carried out.Serum antibodies were tested in some of the close contacts.Results The avian influenza patient had never left Guangzhou in the month prior to disease onset.No contact history with dead or diseased poultry was found. A total of 56 close contacts,including his girl friend,relatives,friends and medical staff who had taken care of him,were brought under medical observation for 7 days but none of them showed signs of infection, Conclusion Unlike SARS,direct contact with patient contracted with avian influenza at the end of incubation period and in the stage of illness through flying droplets,saliva,mucous membrane and skin injuries will not lead to human-to-human transmission,indicating the virus' ability to pass from human to human is limited.
Keywords:Avian influenza  Close contacts  Epidemiological investigation  Transmission
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