临沂地区鼠类携带流行性出血热病毒抗原的初步调查

从临沂地区捕获5种鼠共341只,其中EHF疫区280只。经IFAT检测鼠肺携带EHF病毒抗原,黑线姬鼠带毒率9.5%(16/167),用该地区EHF患者血清与这种EHF病毒抗原进行IFAT检查特异性较高。认为黑线姬鼠为临沂地区EHF的主要传染源。首次从黑线仓鼠检出EHF病毒抗原,带毒率2.4%(1/42),并用10例典型EH F患者双份血清检查,抗体滴度均4倍或4倍以上增高。

A Preliminary Observation on the Antigen of EHF Virus Carried by Rodents in Linyi prefecture

The virus antigen of EHF was detected by IFAT from the lung tissues of A.agrarius from EHF-endemic area, of Linyi prefecture.of the 167 lungs, 16(9.5%) gave positive immunofluorescence. The antigentic specificity was identified obviously by IFAT with convalescent sera from tyopical EHF patients The results indicated that A. agrarius are main infector of EHF in this area, of the 42 lungs of Cicetulus barabersis, one (2.4%) first gave positive. Antigentic specificity of these specimens was detected by IFAT. All of.the paired sera of 10 EHF patients showed 4-fold or more rise of antibody titers.