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饮水中微囊藻毒素对人群健康影响的横断面研究
引用本文:连民,刘颖,俞顺章,陈传炜,周学富,周余春,丁保国,王如鸿.饮水中微囊藻毒素对人群健康影响的横断面研究[J].中华流行病学杂志,2000,21(6):437-440.
作者姓名:连民  刘颖  俞顺章  陈传炜  周学富  周余春  丁保国  王如鸿
作者单位:1. 上海医科大学预防医学研究所环境医学与分子生物研究室,200032
2. 上海医科大学预防医学研究所流行病学教研室,200032
3. 江苏省泰兴市卫生防疫站
基金项目:国家自然科学基金资助项目!(39730380 )
摘    要:目的 初步了解饮水中微囊藻毒素(MC)对人体健康的影响。方法 采用横断面研究方法,在泰兴肝癌高发区两个不同饮水类型的学校里分别随机抽取111名和92名学生,对其进行调查,并采集静脉血,检测血清中乙型肝炎病毒(HBV)感染标志物及血清丙氨酸氨基转移酶(ALT)、γ-谷氨酰转移酶(γ-GT)、碱性磷酸酶(ALP)水平。按照HBV感染进行分层,比较两组人群血清三种酶学水平的差异。结果 两组人群三种酶学指

关 键 词:饮水  微囊藻毒素  流行病学  横断面研究  肝癌
收稿时间:2000/4/7 0:00:00
修稿时间:2000-04-07

A cross-sectional study on the effects of microcystin in drinking water to the health of human beings
LIAN Min,LIU Ying,YU Shunzhang,CHEN Chuanwei,ZHOU Xuefu,ZHOU Yuchun,DING Baoguo and WANG Ruhong.A cross-sectional study on the effects of microcystin in drinking water to the health of human beings[J].Chinese Journal of Epidemiology,2000,21(6):437-440.
Authors:LIAN Min  LIU Ying  YU Shunzhang  CHEN Chuanwei  ZHOU Xuefu  ZHOU Yuchun  DING Baoguo and WANG Ruhong
Institution:Institute of Preventive Medicine, Shanghai Medical University, Shanghai 200032, China.
Abstract:OBJECTIVE: To understand the effects of microcystin (MC) in drinking water on health of human beings. METHODS: In Taixing, a cross-sectional study was conducted in two middle schools with different types of drinking water, from which 111 and 92 students were randomly selected and investigated. Blood samples from all individuals were collected and tested for serum HBsAg, HBeAg, anti-HBe, anti-HBs, anti-HBc with enzyme linked immunoabsorbent assay and for serum alanine aminotransferase (ALT), gamma-glutamyltransferase (gamma-GT) and alkaline phosphatase (ALP) contents by colorimetry. These levels of enzymes in sera were compared after the students were stratified according to the status of HBV infection. RESULT: With the exclusion of the effect of HBV infection, three enzymes levels in sera between two groups of students showed significant differences (P < 0.01), much higher in exposure group than those in control group. CONCLUSION: MC was possibly harmful to human beings in drinking water and induced the contents of some enzymes from the liver of human beings to increase in sera.
Keywords:Drinking  Microcystin  Epidemiology
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