海南百岁老人中肥胖相关指标与抑郁症状风险的关联研究

目的分析百岁老人中腰围、BMI、腰臀比、腰高比、小腿围和腰围小腿围比值(WCR)与其抑郁症状风险间的关联。方法纳入全样本调查的海南百岁老人共1002人。使用GDS-15进行抑郁症状相关风险的调查,使用多元线性回归和logistic回归分析各人体测量指标与抑郁症状风险间的关联强度。结果校正人口学特征(性别、年龄、民族、婚姻状况、文化程度和居住类型)以及生活方式(吸烟和饮酒)相关变量后,总人群中BMI、腰围、腰臀比、腰高比、小腿围和WCR与GDS-15关联的标准β值分别为-0.069、-0.032、0.009、-0.009、-0.099和0.060,其中关于上述β值的检验P值中BMI和小腿围<0.05。随小腿围增加,百岁老人的抑郁症状风险随之降低,OR=0.94(95%CI:0.90~0.98)。而logistic回归分析中显示,随着小腿围的减少和WCR的增加,抑郁症状的风险逐步增加,趋势P值分别为0.038和0.042。结论百岁老人中,中心肥胖(腰围、WCR)与外周肥胖(小腿围)对于抑郁症状具有不同关联,百岁女性中小腿围增加是其抑郁症状风险的保护因素,应关注小腿围较低的老年女性的心理健康问题。

Relationship between obesity related anthropometric indicators and depression risk in Hainan centenarians

Objective To analyze the association of waist circumference,BMI,waist-hip ratio,waist-height ratio,calf circumference and waist-calf circumference ratio(WCR)with depression risk in centenarians in Hainan province.Methods A total of 1002 centenarians in Hainan were selected by cluster sampling.GDS-15 was used to investigate the depression.Multivariate linear regression and logistic regression analyses were conducted to evaluate the correlation between anthropometric indicators and depression risk.Restricted cubic spline was used to analyze and visualize the linear relationship.Results After adjusting demographic characteristics(gender,age,ethnic group,marital status,educational level and type of residence)and lifestyle(smoking and drinking),the standardβof BMI,WC,WHR,WHtR,calf circumference and WCR associated with GDS-15 were-0.069,-0.032,0.009,-0.009,-0.099 and 0.060,respectively,and the P values of BMI and calf circumference were<0.05.With the increase of calf circumference,the risk of depression decreased,OR value was 0.94(95%CI:0.90-0.98),and after adjustment,the results were still significant.Classified variable analysis indicated with the decrease of calf circumference and the increase of WCR,the risk of depression increased gradually,the trend P values were 0.038 and 0.042,respectively.Conclusion Central obesity(waist circumference and WCR)and periphery obesity(calf circumference)have differed effects on depression in centenarians,and increased calf circumference is a protective factor for depression in female centenarians,attention should be paid to the mental health of the elderly women with lower calf circumference.