新型冠状病毒肺炎无症状感染相关研究进展

我国新型冠状病毒肺炎疫情逐步控制,当下对无症状感染者的管理和风险评估成为亟待解决的问题。无症状感染者主要通过密切接触者筛查、聚集性疫情调查、传染源追踪调查、对部分人员开展主动检测等途径发现。目前关于无症状感染者造成疾病传播的风险研究有限,并且缺乏大规模社区人群无症状感染者分布的数据支持。以核酸检测为主要手段的病原学检测适用于已发现的确诊病例和无症状感染者密切接触者等重点人群筛查,应及早开始;而抗体检测更适用于传染来源不明的一般人群中无症状感染者的筛查。对无症状感染者的管理,目前按照“早发现、早报告、早隔离、早治疗”的要求,严格集中隔离和医学观察。

Advances on the asymptomatic infection of COVID-19

The COVID-19 outbreak in China has been gradually controlled. At present, the management and risk assessment of asymptomatic infected cases has become an urgent problem to be addressed. Asymptomatic case is mainly detected by close contact screening, cluster epidemic investigation, infection source tracking investigation, and active detection of target population. Currently, research on the spread risk from asymptomatic cases was limited, and lacking the data relates to the distribution of asymptomatic cases in large community population. Pathogen detection using PCR is suitable for screening in close contacts of confirmed cases and should be started as early as possible. The antibody test is more suitable for screening in general population where the source of infection is unclear. The management of asymptomatic cases now in China focuses on isolation and medical observation according to the guideline of "early detection, early report, early isolation and early treatment".