北京地区儿童青少年体重指数与血压关系的研究

目的 阐明北京地区7～15岁儿童青少年体重指数(或体质指数,BMI)与血压的关系,并为中国肥胖问题工作组(WGOC)提出的中国儿童青少年超重、肥胖分类标准是否能够敏感区分正常体重、超重和肥胖组的血压值提供交叉验证的依据。方法 2000年4～5月,采用分层整群随机抽样对北京地区5155名6～15岁儿童青少年进行肥胖流行特点及其危险因素的横断面调查。按照WGOC推荐的中国儿童青少年超重、肥胖分类标准建议,以及美国疾病预防控制中心推荐的儿童高血压标准诊断儿童高血压,采用Person相关分析、t检验、X~2检验和logistic多因素回归分析等统计学方法,分析了其中7～15岁4982名研究对象的资料。结果(1)在控制了年龄、性别的影响后,7～15岁儿童青少年的BMI与收缩压(SBP)、舒张压(DBP)独立正相关偏相关系数(r)检验P<0.0001,BMI与SBP、DBP的偏r分别为0.323 87和0.245 88;(2)SBP值、DBP值都是肥胖组>超重组>正常体重组,差异有显著性(P<0.001);(3)正常体重、超重、肥胖组间高SBP率、高DBP率、高血压患病率差异有显著性(均为P值<0.0001),与正常体重组相比,超重、肥胖组患高血压的相对危险度(RR)分别为2.96和4.85。超重组和肥胖组的高血压患病率分别高达19.70％和24.22％。(4)logistic多因素回归分析结果提示,年龄和体重对SB

The study on relationship of body mass index and blood pressure in children and adolescents of Beijing

Objective To identify the relationship of body mass index (BMI) and blood pressure in 7-15 years children and adolescents of Beijing so as to provide scientific basis for early prevention of hypertension and to provide evidence for verification on the category criterion of overweight and obesity in children and adolescents of China, recommended by the Working Group on Obesity in China (WGOC) to sensitively distinguish the blood pressure in normal weight, overweight and obesity populations. Methods A cross-sectional survey on epidemiological characteristics of obesity with stratified cluster sampling method carried out in Beijing in April and May, 2000. 5155 students aged 6-15 years were selected as research subjects The category criterion of overweight and obesity in children and adolescents of China was recommended by WGOC, the diagnostic criterion of hypertension in children was recommended by CDC in the USA. Statistics analysis system (SAS 8.1) including partial person correlation analysis, t-test, X~2 test and logistic multi-factors regression analysis was used to analyses the data from 4982 subjects aged 7-15 years. Results (1) after the age and gender were adjusted, the BMI positive correlation with systolic blood pressure (SBP) and diastolic blood pressure (DBP) was found independent in 7-15 years children and adolescents (P<0. 0001) and the partial relation coefficients(r) between BMI and SBP and DBP were 0. 323 87 and 0. 245 88 respectively. (2) the means of SBP and DBP in obesity group were significantly higher then overweight, while overweight was significantly higher then normal weight group (P< 0. 0001). (3) the prevalence rates of hyper-SBP, hyper-DBP and hypertension were significantly different (P<0. 0001). When compared with the normal weight group, the relation risk (RR) for hypertension in overweight group and obesity group were 2. 96 and 4. 85 respectively. The prevalence rates of hypertension in overweight and obesity group wer 19. 70% and 24. 22% respetively. (4) the results of logistic multi- factors regression analysis showed that both age and weight were effecting on hyper-SBP, hyper-DBP and hypertension (P<0.0001). After age was adusted, the RR for hypertension was 2. 62, and their confidence interval (CI) was 2. 36-2. 91 in obesity or overweight, between overweight and normal weight. Conclusion (1) the BMI positive correlation with SBP and DBP was found independent in 7-15 years children and adolescents of Beijing, and the risk for hypertension maybe increased when these people with overweight and obesity, it is very important for hypertension prevention and control that overweight and obesity prevention and control in children and adolescents. (2) the sensitivity of the category criterion of overweight and obesity in children and adolescents of China, recommended by WGOC have been verified on distinguish the blood pressure in normal weight, overweight and obesity populations.