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婚前接种乙型肝炎疫苗阻断HBV母婴传播的效果观察
引用本文:胡昭烈,滕洪范,韩敏,王秀英,刘敬珍.婚前接种乙型肝炎疫苗阻断HBV母婴传播的效果观察[J].中华流行病学杂志,1994,15(6):346-348.
作者姓名:胡昭烈  滕洪范  韩敏  王秀英  刘敬珍
作者单位:山东淄博第二卫生学校,山东淄博卫生学校,齐鲁石化中心医院
摘    要:6年追踪随访婚前接种乙肝疫苗和对照组母亲的新生儿42人,结果免疫成功母亲的婴儿6个月血清抗-HBs阳性率为90.00%(9/10),且无1人感染HBV,而两组婚前和婚后HBsAg、HBsAg/HBeAg阳性母亲的婴儿依次为20.00%(2/10)及18.18%(4/22),显著低于前者(P<0.01),但HBsAg阳性率各为70.00%(7/10)、68.18%(15/22)。表明婚前乙肝疫苗免疫的“双阻断”作用可部分打破HBV“夫妇-母婴-人群”的传播链。

关 键 词:HBV  乙肝疫苗
收稿时间:1993/10/6 0:00:00
修稿时间:1994/1/2 0:00:00

Obeservation on Prevention of Hepatitis B Virus Transmission from Mother to Baby by Hepatitis B Vaccine
Hu Zhaolie,Teng Hongfan,Han Min.Obeservation on Prevention of Hepatitis B Virus Transmission from Mother to Baby by Hepatitis B Vaccine[J].Chinese Journal of Epidemiology,1994,15(6):346-348.
Authors:Hu Zhaolie  Teng Hongfan  Han Min
Institution:Hu Zhaolie,Teng Hongfan,Han Min,et al.Zibo 2nd Health School,Shandong Province,255015
Abstract:Forty-two new-born infants whose mothers had been given HBV vaccine before marriage were undergone medical examination for six years. The results showed that the six-month seroconversion rates of anti-HBs among those infants, whose mothers had been immunized successfully, were 90.00% (9/10), and no one was infected by HBV. But the rates of those infants whose mothers were found to be HBsAg(+) and HBsAg/HBeAg(+) before or after marriage were 20.00% (2/10) and 18.18% (4/22), respectively, being much lower than the former. The rates of HBsAg(+) were 70.00% (7/10) and 68.18% (15/22), respec-tively. This led to the conclusion that immunization with HBV vaccine before marriage will partly break the HBV transmission chain of "couples-mother and her baby-population".
Keywords:HBV Vaccines  
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