浙江省鼠及主要鼠传疾病综合监测试点研究

目的 探索病媒生物及相关疾病综合监测模式.方法 在浙江省选择2个病媒生物监测点进行现场研究,整合鼠及鼠疫、肾综合征出血热(HFRS)和钩端螺旋体病(钩体病)监测方案,协调机构和人员在市和县两个层面上开展综合监测;鼠类综合监测时间为2009年6、8、10月,采用鼠笼法捕鼠.结果 在浙江省丽水市和龙游县完成鼠密度、季节消长和鼠传疾病综合监测.2009年丽水市报告钩体病3例,发病率为0.13/10万,HFRS 58例,发病率为2.44/10万;龙游县报告钩体病2例,发病率为0.49/10万,HFRS 1例,发病率为0.25/10万.两地区均无鼠疫病例报告.丽水市共捕获鼠类91只,鼠密度为4.17%;龙游县捕获鼠类37只,鼠密度为1.18%.丽水市以黑线姬鼠为主,龙游县以黄胸鼠为主.丽水市对493只鼠进行媒介昆虫监测,染蚤鼠共51只,染蚤率为10.34%.两地区鼠疫病原学及血清学监测结果均为阴性.丽水市HFRS抗原阳性率为10.42%,明显高于龙游县的4.59%.两地阳性鼠种均为黑线姬鼠.龙游县鼠血标本HFRS抗体阳性率为3.70%;丽水市鼠肾培养钩体阴性,龙游县鼠肾钩体阳性率为0.98%;龙游县鸭血钩体抗体阳性率为80%.结论 对鼠群及鼠疫、HFRS和钩体病开展病媒生物综合监测是可行的,建议加强鼠及鼠传疾病综合监测.

Study on the integrated monitoring program regarding mouse and main mouse-borne disease in Zhejiang province

Objective To study the integrated monitoring program regarding mouse and plague, hemorrhagic fever of renal syndrome(HFRS)and leptospirosis. Methods Integrated monitoring plan was used. A designated office coordinated 5 departments' actions within the Zhejiang Provincial Center for Disease Control and Prevention(CDC). Cage-trapping method was conducted to monitor the density of mice from June to October, respectively. Results Lishui municipal CDC had finished the integrated monitoring program on mouse and mouse-borne disease while the Longyou CDC had finished the field investigation, using the integrated monitoring program.Specimens were sent to provincial CDC. The integrated monitoring program needed more number of personnel and better coordination. Lishui reported 3 leptospirosis cases and 58 HFRS cases in 2009,with the incidence rates as 0.13 and 2.44 per 100 000, respectively. Longyou reported 2 leptospirosis case and 1 HFRS cases in 2009, with the incidence rates as 0.49 and 0.25 per 100 000, respectively.Lishui and Longyou had no plague case. Lishui caught 91 mice in 2009 and the density was 4.17%.Longyou caught 37 mice in 2009, with the density as 1.18 percent. Most mice caught from Lishui were Apodemus agrarius and the next was Mus musculus. In Longyou the Rattus tanezumi ranked the first, followed by Apodemus agrarius. The positive rate of HFRS antigen in Lishui and Longyou were 10.42% and 4.59% respectively. The positive rate of HFRS antibody in Longyou was 3.70%. The culture positive rate of leptospirosis in mouse renal of Lishui and Longyou were 0 and 0.98%respectively. The culture positive rate of leptospirosis in pig renal, duck renal, frog renal and cattle urine of Longyou was 0. The culture positive rate of leptospirosis in duck blood of Longyou was 80%.Conclusion The integrated monitoring program on mouse and mouse-borne disease seemed to be feasible and could promote the integrated surveillance and control program on mouse and mouse-borne diseases in China.