| 上海市浦东新区腹泻患者气单胞菌流行特征及毒力基因研究 |
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| 引用本文： | 王闻卿,王多春,朱林英,傅益飞,郝莉鹏,许学斌,苏靖华,傅慧琴,叶楚楚,孙乔,郑英杰.上海市浦东新区腹泻患者气单胞菌流行特征及毒力基因研究[J].中华流行病学杂志,2016,37(3):402-405. |
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| 作者姓名： | 王闻卿 王多春 朱林英 傅益飞 郝莉鹏 许学斌 苏靖华 傅慧琴 叶楚楚 孙乔 郑英杰 |
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| 作者单位： | 200136 上海市浦东新区疾病预防控制中心微生物检验科;102206 北京, 中国疾病预防控制中心传染病预防控制所, 传染病预防控制国家重点实验室;200136 上海市浦东新区疾病预防控制中心微生物检验科;200136 上海市浦东新区疾病预防控制中心传染病防治与消毒管理科;200136 上海市浦东新区疾病预防控制中心微生物检验科;200336 上海市疾病预防控制中心微生物检验科;200136 上海市浦东新区疾病预防控制中心微生物检验科;200136 上海市浦东新区疾病预防控制中心微生物检验科;200136 上海市浦东新区疾病预防控制中心传染病防治与消毒管理科;200136 上海市浦东新区疾病预防控制中心传染病防治与消毒管理科;200032 上海, 复旦大学公共卫生学院教育部公共卫生重点实验室, 复旦大学公共卫生学院卫生微生物学教研室 |
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| 摘 要： | 目的 了解上海市浦东新区腹泻患者气单胞菌流行特征及毒力基因特征。方法 2012年1－12月,在上海市浦东新区12家腹泻监测点医院对符合病例定义的病例采集粪便,进行13种腹泻病原体检测,对分离到的气单胞菌株进行5种与腹泻相关的毒力基因(ast、aerA、act、alt、hlyA)检测。结果 2 533例腹泻患者中,101例感染气单胞菌,阳性率为4.0%,分离到嗜水气单胞菌17株(18.8%),维隆气单胞菌温和变种44株(52.5%),豚鼠气单胞菌12株(29.7%)。44例患者为气单胞菌与其他病原体混合感染。夏季为高发季节,≥20岁人群高发。71例(70.3%)患者临床症状为水样便,20例(19.8%)患者出现呕吐症状,11例(10.9%)有发热症状。95.0%的气单胞菌携带毒力基因,hlyA基因阳性率为5.9%,aerA基因阳性率为6.9%,act基因阳性率为67.3%,alt基因阳性率为42.6%,ast基因阳性率为13.9%。结论 浦东新区腹泻患者中气单胞菌感染阳性率较高,并存在较高比例的混合感染。绝大多数气单胞菌都携带毒力基因,且分布存在差异性。
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| 关 键 词： | 气单胞菌 腹泻 混合感染 毒力基因 |
| 收稿时间： | 2015/8/5 0:00:00 |
Infection status and virulent genes of Aeromonas in diarrhea patients in Pudong New Area, Shanghai |
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| Wang Wenqing,Wang Duochun,Zhu Linying,Fu Yifei,Hao Lipeng,Xu Xuebin,Su Jinghu,Fu Huiqin,Ye Chuchu,Sun Qiao and Zheng Yingjie.Infection status and virulent genes of Aeromonas in diarrhea patients in Pudong New Area, Shanghai[J].Chinese Journal of Epidemiology,2016,37(3):402-405. |
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| Authors: | Wang Wenqing Wang Duochun Zhu Linying Fu Yifei Hao Lipeng Xu Xuebin Su Jinghu Fu Huiqin Ye Chuchu Sun Qiao and Zheng Yingjie |
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| Institution: | Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;State Key Laboratory for Communicable Disease Control and Prevention, Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China;Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Department of Microbiology of Shanghai Municipal Center for Disease Control and Prevention, Shanghai 200336, China;Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Department of Microbiology of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Department of Infectious Disease Control and Prevention and Disinfection Management Section of Pudong New Area Center for Disease Control and Prevention, Shanghai 200136, China;Key Laboratory of Public Health Safety of the Ministry of Education, Department of Public Health Microbiology, Fudan University School of Public Health, Shanghai 200032, China |
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| Abstract: | |
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| Keywords: | Aeromonas Diarrhea Co-infection Virulent gene |
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