新疆、西藏地区居民肥胖类型与10年冠心病发病风险关系的研究

目的 探讨我国新疆、西藏地区居民肥胖类型以及与10年冠心病发病风险关系。方法 采用多阶段分层随机抽样的方法，共抽取新疆、西藏两地≥35岁研究对象7 631人，其中5 802人纳入本研究分析。结果 研究对象的普通肥胖、腹型肥胖、内脏肥胖和混合型肥胖患病率分别为0.53%、12.62%、10.08%和42.35%。其中混合肥胖中同时满足3种肥胖类型诊断标准的研究对象占58.65%（1 441/2 457）。男、女性10年冠心病患病风险分别为（3.05±4.14）%和（1.42±2.37）%（男性高于女性，P<0.000 1）。混合型肥胖研究对象高等级冠心病发病风险所占比例为30.16%，显著高于普通肥胖（19.35%）、腹型肥胖（28.01%）和内脏肥胖（18.46%）。多因素分析校正混杂因素后显示，混合型肥胖人群10年冠心病发病风险高于其他肥胖类型（OR=2.889，95% CI：2.525～3.305），其中BMI和腰围两项指标均异常的研究对象10年冠心病风险更高（OR=3.168，95% CI：2.730～3.677）。结论 肥胖问题在新疆、西藏地区较为严重，男性、混合型肥胖（特别是BMI与腰围均异常）人群10年冠心病发病风险高。

Association between the types of obesity and the 10-year-coronary heart disease risk, in Tibet Autonomous Region and Xinjiang Uygur Autonomous Region

Objective To investigate the association between types of obesity and the 10-year-coronary heart disease risk in Tibet and Xinjiang of China. Methods Using the multi-stage random sampling method, 7 631 participants aged 35 or older were examined under the International Standardized Examination process but with only 5 802 were eligible for analysis, in the 2015-2016 season. Results The prevalence rates of general obesity, central obesity, visceral obesity and compound obesity were 0.53%, 12.62%, 10.08% and 42.35%, respectively. Out of all the compound obesity cases, 58.65% (1 441/2 457) of them appeared as having all types of obesity in our study. Risk related to the 10-year-coronary heart disease was higher in men than in women(3.05±4.14)% vs. (1.42±2.37)%, P<0.000 1. Compound obesity (30.16%) showed the highest proportion on the risk of 10-year-coronary heart disease than central obesity (28.01%), visceral obesity (18.46%) or the general obesity (19.35%). After adjustment for confounding factors, results from the multivariate analysis showed the risk in compound obesity was higher than central obesity, visceral obesity or general obesity and was associated with the highest risk on the 10-year-coronary heart disease (OR=2.889, 95%CI:2.525-3.305). People with anomalous BMI and WC seemed to have had the higher risk (OR=3.168, 95%CI:2.730-3.677). Conclusions Obesity was popular in the residents of Tibet and Xinjiang areas of China. Men and people with compound obesity (especially both BMI and WC were abnormal) seemed to carry greater risk on the 10-year- coronary heart disease.