戊型肝炎病人IgG抗体持续时间观察

目的 ]　了解本市戊型肝炎病人IgG抗体持续时间情况。　方法 ]　选择 1992～ 2 0 0 2年本市经临床和血清确诊为戊型肝炎的 497例病人作为本次调查对象。采集调查对象血清用酶联免疫吸附法 (ELISA)检测抗HEV -IgG。　 结果 ]　调查对象抗HEVIgG总阳性率为 65 .4% ,当年发病者IgG抗体阳性率保持在较高水平 (达 88.9% ) ,随着发病年限的增长 ,发病者的抗HEVIgG基本保持在一个较稳定的水平 (约 60 %上下 ) ;发病者体内 10年后仍有抗HEVIgG(阳性率 3 3 .3 % )。　 结论 ]　戊型肝炎病人发病后IgG抗体持续时间长短不一 ,一般可以维持较长时间

Observation on persistence of Anti-HEV IgG in hepatitis E patients

Objective To observe the persistence of anti-HEV IgG of hepatitis E patients in Shanghai. Methods] Four hundred and ninety seven cases diagnosed as HE by clinics and serology during 1992 to 2002 were used for study. The blood samples of each case were collected and detected by using ELISA. Results] The positive rate of anti-HEV IgG in the 497 cases was 65.4%. The rate of positive anti-HEV IgG was high in the same year of onset (88.9%), it declined gradually but maintained at a steady level(about 60%) year by year.One third could be detected over 10 years after onset. Conclusion] Anti-HEV IgG can maintain in patients for a long time, but there are individual differences.