老年AS性脑梗死治疗中阿托伐他汀剂量与疗效的关系研究

目的研究老年AS性脑梗死治疗中阿托伐他汀剂量与疗效的关系。方法选取医院神经内科2017年6月—2018年5月收治的70例老年动脉粥样硬化(atherosclerosis,AS)性脑梗死患者作为研究对象,按照抽签法将其均分为两组(n=35),A组采用10 mg阿托伐他汀治疗,B组采用40 mg阿托伐他汀治疗,对比两组治疗效果。结果治疗后,两组美国国立卫生研究院卒中量表(NIH stroke scale,NIHSS)评分均有所下降,BI指数评分上升,组内前后对比差异显著(P<0.05),B组NIHSS评分略低于A组,BI指数略高于A组,但差异无统计学意义(P>0.05);B组治疗有效率明显高于A组(P<0.05)。结论老年AS性脑梗死患者采用40 mg阿托伐他汀治疗,更好的改善神经功能缺损程度和日常生活活动能力,且治疗有效率较高。

Study on the Relationship Between Atorvastatin Dose and Curative Effect in the Treatment of AS Cerebral Infarction in the Elderly

Objective To study the relationship between atorvastatin dose and efficacy in the treatment of AS cerebral infarction in the elderly.Methods 70 elderly patients with AS cerebral infarction admitted and treated in the department of neurology of our hospital from June 2017 to May 2018 were selected AS patients.Methods 70 cases of elderly patients with AS cerebral infarction admitted and treated in the department of neurology of our hospital from June 2018 to May 2019 were selected AS research objects.All of them were divided into two groups(n=35)according to the draw method.Group A was treated with 10mg atorvastatin,group B with 40 mg atorvastatin,and the therapeutic effects of the two groups were compared.Results After treatment,the NIHSS scores of both groups decreased,and the BI index scores increased.There was A significant difference between the two groups before and after treatment(P<0.05).The NIHSS scores of group B were slightly lower than those of group A,and the BI index was slightly higher than those of group A,but the difference was not statistically significant(P>0.05).The effective rate of group B was significantly higher than group A(P<0.05).Conclusion Elderly patients with AS cerebral infarction treated with 40 mg of atorvastatin can better improve the degree of neurological deficit and activities of daily living,and the treatment efficiency is higher.