中西医结合治疗卵巢储备功能减退患者成功妊娠二例并文献复习

卵巢储备功能减退（diminished ovarian reserve，DOR）是卵巢因素所致不孕症的主要原因之一，西医临床治疗方法主要依赖于口服提高卵巢储备功能的药物、人工激素周期替代疗法和辅助生殖技术助孕，中医运用补肾健脾法治疗DOR具有不良反应少、疗效持久、治疗手段多样化等优势。报告2例在常规西医治疗基础上应用中医补肾健脾法综合治疗DOR患者成功妊娠的情况，强调个体化中西医结合治疗方案对于解决疑难病证的重要性，为临床应用中医药治疗DOR患者提供证据。

Case Report of Pregnancy in Two Patients with Diminished Ovarian Reserve Treated with Traditional and Western Medicine,and Literature Review

The diminished ovarian reserve (DOR) is one of the main causes of infertility caused by ovarian factors. The clinical treatment with Western Medicine mainly relies on the oral drugs to improve the ovarian reserve function, artificial hormone cycle replacement and assisted reproductive technology to help pregnancy. The method of Tonifying Kidney and Strengthen Spleen Therapy in Traditional Chinese Medicine (TCM) has many advantages in improving the ovarian reserve function, such as low adverse reactions, long-lasting curative effect and diversified methods. In this article, two cases of DOR patients were reported who were successfully treated with the comprehensive treatment of Tonifying Kidney and Strengthen Spleen Therapy of TCM on the basis of conventional Western Medicine. We emphasized the importance of formulating a targeted and individualized treatment plan of the integrated TCM and Western Medicine for solving difficult diseases. This article provides a new evidence of the comprehensive treatment with TCM and Western Medicine in DOR patients.