首页 | 本学科首页   官方微博 | 高级检索  
     

肥胖型PCOS患者的生物学特征和临床特征
引用本文:王娇剑,鲁娣,陈然然,宋殿荣. 肥胖型PCOS患者的生物学特征和临床特征[J]. 国际生殖健康/计划生育杂志, 2022, 41(3): 230-235. DOI: 10.12280/gjszjk.20220067
作者姓名:王娇剑  鲁娣  陈然然  宋殿荣
作者单位:301617 天津中医药大学(王娇剑);天津中医药大学第二附属医院妇科(鲁娣,陈然然,宋殿荣)
摘    要:多囊卵巢综合征(polycystic ovary syndrome,PCOS)是一种内分泌代谢紊乱综合征,临床表现高度异质性。肥胖是PCOS异质性临床表现之一,超过50%的PCOS患者超重或肥胖。肥胖型PCOS主要表现为高雄激素血症、中心型肥胖和糖脂代谢紊乱,非肥胖型PCOS主要表现为黄体生成激素(luteinizing hormone,LH)水平异常升高。尽管肥胖型和非肥胖型PCOS均存在内分泌代谢异常,然而肥胖可加重PCOS糖脂代谢紊乱;肥胖型PCOS还表现脂肪代谢的异常。综述肥胖型PCOS患者的临床特征、性激素水平、糖脂代谢特征,旨在为肥胖型和非肥胖型PCOS患者新的分型诊治提供参考。

关 键 词:多囊卵巢综合征  肥胖症  性腺甾类激素  葡萄糖代谢障碍  脂代谢障碍
收稿时间:2022-02-09

Biological and Clinical Characteristics of Obese PCOS Patients
WANG Jiao-jian,LU Di,CHEN Ran-ran,SONG Dian-rong. Biological and Clinical Characteristics of Obese PCOS Patients[J]. Journla of International Reproductive Health/Family Planning, 2022, 41(3): 230-235. DOI: 10.12280/gjszjk.20220067
Authors:WANG Jiao-jian  LU Di  CHEN Ran-ran  SONG Dian-rong
Affiliation:Tianjin University of Traditional Chinese Medicine, Tianjin 301617, China (WANG Jiao-jian); Department of Gynecology, Second Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China (LU Di, CHEN Ran-ran, SONG Dian-rong)
Abstract:Polycystic ovary syndrome (PCOS) is an endocrine and metabolic syndrome with highly heterogeneous manifestations. Obesity is one of the heterogeneous manifestations of PCOS, and more than 50% of PCOS patients are overweight or obese. Obese PCOS is characterized mainly by hyperandrogenism, central obesity and disturbed glucose and lipid metabolism, while non-obese PCOS is characterized mainly by abnormally elevated level of luteinizing hormone (LH). Although the endocrine metabolic abnormalities are present in both obese and non-obese PCOS, obesity exacerbates the disturbed glycolipid metabolism in PCOS patients. The obese PCOS also expresses the abnormality of lipid metabolism. In this review, we summarizethe clinical features, sex hormone levels and glycolipid metabolism of obese PCOS patients, so as to provide a reference for the new diagnosis and treatment of obese and non obese patients with PCOS.
Keywords:Polycystic ovary syndrome  Obesity  Gonadal steroid hormones  Glucose metabolism disorders  Lipid metabolism disorders  
本文献已被 维普 万方数据 等数据库收录!
点击此处可从《国际生殖健康/计划生育杂志》浏览原始摘要信息
点击此处可从《国际生殖健康/计划生育杂志》下载全文
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号