深圳市福田区艾滋病患者抗病毒治疗相关情况分析

目的通过对深圳福田区符合艾滋病免费抗病毒治疗患者的流行病学资料分析，以探讨对治疗依从性可能存在的影响因素。方法收集福田区所有需要接受抗病毒治疗艾滋病患者基本情况及接受治疗后临床资料分析其流行病学特征。结果福田区累计174名患者需接受治疗，目前134人在治，治疗覆盖率77．0％。以中年为主，男女性别比2．3：1，初中及以下文化程度占63．2％，感染途径主要为性传播途径（占87．4％）。开始治疗前无明显临床症状的人仅占12．1％，84．5％的患者CD4＋T淋巴细胞计数≤200个／μ1；进入治疗中35．1％会出现药物副反应，9．7％出现机会性感染或者新疾病。结论艾滋病感染者需探讨更有效的早发现及治疗的模式。

Analysis on epidemiological and clinical characteristics of HIV antiretroviral treatment patients in Futian District,Shenzhen City

Objective To analyze the epidemiological data about the patients with free antiretroviral therapy for HIV/AIDS in Futian District, Shenzhen City so as to explore the factors affecting patients＇ compliance to medication. Methods The epide- mioIogical and clinical data on the patients with free antiretroviral therapy for HIV/AIDS in Futian District were collected and an- alyzed. Results A total of 174 patients needed to be treated in Futian District. 134 patients received the treatment, with the medication coverage of 77.0 %. Most patients were the middle- aged, and the ratio of male to female was 2.3：1. Patients hav- ing an education background of junior middle school and below accounted for 63.2%. 87.4% of the patients were infected with HIV through sexual transmi~ion. Only 12.1% of the patients showed no obvious clinical symptoms before starting treatment. Patients whcxse CD4 ＋ T cell counts were ≤ 200 cells/μ4 accounted for 84.5 %. Adverse drug reactions appeared in 35.1% of the patients during the treatment, and opportunistic infection or new disease occurred in 9.7 % of them. Conclusions Earlier de- tection and diagnosis of HIV- positive easels should be reinforced.