| 联合检测血管内皮功能、D-二聚体在脑梗死中的临床意义 |
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| 引用本文： | 白春洋,赵玉峰.联合检测血管内皮功能、D-二聚体在脑梗死中的临床意义[J].现代预防医学,2011,38(10):1998-1999. |
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| 作者姓名： | 白春洋 赵玉峰 |
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| 作者单位： | 河南大学淮河医院,开封,475000 |
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| 摘 要： | 目的]探讨联合监测血管内皮功能内皮素(ET-1)、一氧化氮(NO)]及D-二聚体(D-dimer)对脑梗死患者诊断的临床意义。方法]选择150例发病24h内的脑梗死患者,100例健康对照组,采用全自动生化分析仪和ELISA法分别检测内皮功能NO,ET-1]和D-二聚体含量。结果]脑梗死患者血浆ET-1、D-二聚体含量明显增高,NO含量明显降低;与健康对照组比较,差异有统计学意义(P﹤0.01)。结论]脑梗死患者NO生成减少,ET-1生成增加,从而促进血管内血栓形成增加脑梗死发生的危险性;而脑梗死早期血浆D-二聚体明显升高,三者联合检测可为脑梗死的早期诊断和预防性治疗提供可靠的依据。
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| 关 键 词： | 脑梗死 内皮素 一氧化氮 D-二聚体 |
THE CLINICAL SIGNIFICANCE ON EXPLORING THE FUNCTION OF ENDOTHELIAL AND THE LEVEL OF D-DIMER IN PATIENTS WITH CEREBRAL INFRACTION |
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| BAI Chun-yang,ZHAO Yu-feng.THE CLINICAL SIGNIFICANCE ON EXPLORING THE FUNCTION OF ENDOTHELIAL AND THE LEVEL OF D-DIMER IN PATIENTS WITH CEREBRAL INFRACTION[J].Modern Preventive Medicine,2011,38(10):1998-1999. |
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| Authors: | BAI Chun-yang ZHAO Yu-feng |
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| Institution: | BAI Chun-yang,ZHAO Yu-feng.(Huaihe Hospital,Henan University,Kaifeng 475000,China) |
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| Abstract: | Objective]To explore the clinic significance of the change of the levels of endotheline-1(ET-1),nitric oxide(NO)and D-dimer in the serum of the patients with cerebral infraction(CI).Methods]There were 150 cases with CI in 24 hours and 100 cases were selected as normal people.By automatic biochemistry analyzer and ELISA method,the level of ET-1,NO and D-dimer were detected.Results]The level of ET-1 and D-dimer in blood of patients with CI was higher than that of normal obviously,and the level of NO was lo... |
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| Keywords: | Cerebral Infraction(CI) Endotheline-1(ET-1) Nitric oxide(NO) D-dimer |
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