65岁以上老年空腹血糖受损人群2年转归及影响因素分析

目的 探讨65岁以上空腹血糖受损人群2年后自然转归及影响因素。方法 对2019年武进区65岁以上老年人健康体检时发现的空腹血糖受损人群，2年后再次进行健康体检，健康体检内容包括问卷调查、体格检查和实验室检查。采用logistic回归来探讨相关影响因素分析。结果 共计14 790空腹血糖受损者完成2年后的体检，其中6 285(42.49%)人血糖转归正常，5 697(38.52%)人血糖仍为空腹血糖受损，2 808(18.99%)人发展为糖尿病患者。多因素逐步logistic回归结果显示，女性（OR=1.13,95%CI:1.02～1.24）、高血压（OR=1.36,95%CI:1.24～1.50）、FPG(OR=12.65,95%CI:10.63～15.05)、TG(OR=1.07,95%CI:1.04～1.11)和BMI(OR=1.05,95%CI:1.04～1.06)是空腹血糖受损人群进展为糖尿病的危险因素；饮酒（OR=0.82,95%CI:0.72～0.94）、体育锻炼（OR=0.80,95%CI:0.73～0.87）、HDL-C(OR=0.62,95%CI:0.58～0.67)...

Analysis of 2-year outcome and influencing factors in elderly patients over 65 with impaired fasting blood glucose

Objective To investigate the natural outcome of people over 65 years old with impaired fasting glucose (IFG) after 2 years and the influencing factors. Methods The elderly over 65 years old in Wujin District who had IFG during the physical examination in 2019 were examined again two years later. The physical examination included questionnaire, physical examination, and laboratory examination. Logistic regression was used to explore the influencing factors. Results A total of 14 790 patients with IFG completed physical examination 2 years later, of which 6 285 (42.49%) returned to normal blood glucose, 5 697 (38.52%) still had impaired fasting blood glucose, and 2 808 (18.99%) developed diabetes. The results of multivariate stepwise logistic regression showed that female (OR=1.13, 95%CI: 1.02-1.24), hypertension (OR=1.36, 95%CI: 1.24-1.50), FPG (OR=12.65, 95%CI: 10.63-15.05), TG (OR=1.07, 95%CI: 1.04-1.11), and BMI (OR=1.05, 95%CI: 1.04-1.06) were risk factors for the progression of diabetes in people with IFG (OR=0.82, 95%CI: 0.72-0.94), physical exercise (OR=0.80, 95%CI: 0.73-0.87), and HDL-C (OR=0.62, 95%CI: 0.58-0.67) were protective factors. After adjusting for age, sex, smoking, drinking, physical exercise, education, hypertension, and baseline fasting blood glucose, the risk factors included weight gain, waist circumference, TC, TG, and LDL-C. Conclusion People over 65 years old with IFG have a higher risk of developing diabetes. Female, hypertension, FPG, TG, and BMI are the risk factors. It is necessary to control body weight, waist circumference, and blood lipids to prevent and slow down the occurrence of diabetes.