种子招募的静脉吸毒人群高危行为及HIV、HCV和梅毒感染特征

目的：了解在四川省凉山州地区队列组建中不同招募途径的静脉吸毒人群高危行为及HIV、HCV和梅毒感染特征情况。方法：在队列组建时调查研究对象的招募方式、社会人口学和高危行为特征，采集血样检测HIV、HCV和梅毒感染情况。结果：在379名招募的静脉吸毒人群中，309人（81．5％）是通过种子推荐来的，70人（18．5％）是从其他途径获得信息来的。种子介绍的与其他方式招募的研究对象在民族构成、近3个月静脉注射吸毒频率、近3个月海洛因混合安定使用频率差异有统计学意义。近3个月毒品使用的其他方式、注射器具共用情况、性行为和血样HIV、HCV和梅毒检测结果上差异无统计学意义（P〉O,05）。结论：采用应答驱动抽样方法是招募静脉吸毒人员行之有效的方法，但尚需进一步探讨其对参加者高危行为特征与血清学检测结果的影响。

A SURVEY OF RESPONDENT- DRIVEN SAMPLING IN COHORT STUDY OF INJECTION DRUG USERS

Objective:To study baseline high risk behaviors and results of cohort study among injection drug users(IDUs)recruited from community using peer recruiting method in respondent-driven sampling in Liangshan,Sichuan province.Methods:Baseline high risk behaviors of IDUs were investigated by using recruited structural questionnaire in order to find out differences between peer recruiting and other methods.Results:309 of the 379 subjects(81.5%)were enrolled by peer recruiting,and 70 of them(18.5%)enrolled by other methods.Only ethnicity composition,frequency of drug injection in the past 3 months and frequency of heroin injection with diazepam in the past 3 months were found to be significantly associated with recruiting methods.Other drug using methods,sharing of syringe for drug injection in the past 3 months,sexual behavior in the past 3 or 6 months,HCV,HIV and syphilis infection were found to be no significant statistical differences between peer recruiting and other methods.Conclusion:Peer recruitment of respondent-driven sampling is probably an effective method for recruiting IDUs.Further studies should be conducted to get its influence on detection of plasma samples and high risk behaviors of the participant.