| 干细胞治疗卵巢早衰研究进展 |
| |
| 作者姓名： | 王丽娟 梁晓磊 杨永秀 |
| |
| 作者单位： | 兰州大学第一临床医学院;兰州大学第一医院妇产科 |
| |
| 摘 要： | 早发性卵巢功能不全(premature ovarian insufficiency,POI)也被称为卵巢早衰,作为女性不孕症的主要原因之一,受到广泛关注,主要表现为低雌激素水平和高促性腺激素水平。POI的病因及机制复杂,目前无统一定论,在治疗上也主要采用补充雌激素等综合治疗。随着干细胞研究的深入,干细胞治疗POI成为新的关注点,本文对POI的病因及不同来源干细胞治疗POI的作用机制做一综述,为后续的研究提供参考。
|
| 关 键 词： | 干细胞 间充质干细胞 早发性卵巢功能不全 卵巢早衰 |
Advances in stem cell therapy for premature ovarian failure |
| |
| Authors: | Wang Lijuan Liang Xiaolei Yang Yongxiu |
| |
| Institution: | (The First Clinical Medical College of Lanzhou University,Lanzhou 730000,China;Department of Obstetrics and Gynecology,the First Hospital of Lanzhou University,Key Laboratory for Gynecologic Oncology Gansu Province,Lanzhou 730000,China) |
| |
| Abstract: | Premature ovarian insufficiency(POI)is also known as premature ovarian failure,as one of the main causes of female infertility,and has been widely concerned,mainly manifested by low estrogen levels and high gonadotropin levels.The etiology and mechanism of POI are complex,and there is no consensus at present.With the deepening of stem cell research,stem cell therapy for POI has become a new focus.This paper summarizes the etiology of POI and the mechanism of action of stem cell therapy for POI from different sources,providing reference for future research. |
| |
| Keywords: | Stem cells Mesenchymal stem cells Premature ovarian insufficiency Premature ovarian failure |
| 本文献已被 维普 等数据库收录！ |
|
