Carotid Atherosclerosis Is Associated With Poorer Hearing in Older Adults |
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| Authors: | Pauline H Croll Daniel Bos Meike W Vernooij Banafsheh Arshi Frank R Lin Robert J Baatenburg de Jong M Arfan Ikram André Goedegebure Maryam Kavousi |
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| Institution: | 1. Department of Otorhinolaryngology, Head and Neck Surgery, Erasmus University Medical Center, Rotterdam, the Netherlands;2. Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands;3. Department of Radiology and Nuclear Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands;4. Department of Otolaryngology-Head & Neck Surgery and Epidemiology, Johns Hopkins School of Medicine and Bloomberg School of Public Health, Baltimore, MD |
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| Abstract: | ObjectivesCardiovascular disease may be linked to hearing loss through narrowing of the nutrient arteries of the cochlea, but large-scale population-based evidence for this association remains scarce. We investigated the association of carotid atherosclerosis as a marker of generalized cardiovascular disease with hearing loss in a population-based cohort.DesignCross-sectional.SettingA population-based cohort study.Participants3724 participants mean age: 65.5 years, standard deviation (SD): 7.5, 55.4% female].MethodsUltrasound and pure-tone audiograms to assess carotid atherosclerosis and hearing loss.ResultsWe investigated associations of carotid plaque burden and carotid intima-media thickness (IMT) (overall and side-specific carotid atherosclerosis) with hearing loss (in the best hearing ear and side-specific hearing loss) using multivariable linear and ordinal regression models. We found that higher maximum IMT was related to poorer hearing in the best hearing ear difference in decibel hearing level per 1-mm increase in IMT: 2.09 dB, 95% confidence interval (CI): 0.08, 4.10]. Additionally, third and fourth quartile plaque burden as compared to first quartile was related to poorer hearing in the best hearing ear (difference: 1.06 dB, 95% CI: 0.04, 2.08; and difference: 1.55 dB, 95% CI: 0.49, 2.60, respectively). Larger IMT (difference: 2.97 dB, 95% CI: 0.79, 5.14), third quartile plaque burden compared to first quartile (difference: 1.24 dB, 95% CI: 0.14, 2.35), and fourth plaque quartile compared to first quartile (difference: 2.12 dB, 95% CI: 0.98, 3.26) in the right carotid were associated with poorer hearing in the right ear.Conclusions and ImplicationsCarotid atherosclerosis is associated with poorer hearing in older adults, almost exclusively with poorer hearing in the right ear. Based on our results, it seems that current therapies for the prevention of cardiovascular disease may also prove beneficial for hearing loss in older adults by promoting and maintaining inner ear health. |
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| Keywords: | Address correspondence to André Goedegebure PhD Department of Otorhinolaryngology Head and Neck Surgery Erasmus University Medical Center P O Box 2040 3000CA Rotterdam the Netherlands Aging carotid atherosclerosis hearing loss plaque intima media thickness |
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