Flu and pertussis vaccination during pregnancy in Geneva during the COVID-19 pandemic: A multicentric,prospective, survey-based study |
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| Institution: | 1. Department of Pediatrics, Gynecology and Obstetrics, University Hospitals of Geneva (HUG), Geneva, Switzerland;2. Hôpital de la Tour, Geneva, Switzerland;3. Faculty of Medicine, University of Geneva, Switzerland;4. Clinique des Grangettes, Geneva, Switzerland;5. Clinique Générale Beaulieu, Geneva, Switzerland;6. Maison de naissance la Roseraie, Geneva, Switzerland;7. CRC and Division of Clinical Epidemiology, Department of Health and Community Medicine, University Hospitals of Geneva (HUG), Switzerland;8. Unit of Population Epidemiology, Department of Primary Care, University Hospitals of Geneva (HUG), Geneva, Switzerland |
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| Abstract: | ObjectiveTo determine pertussis and influenza vaccination coverage during pregnancy among women delivering in all the maternities of Geneva (Switzerland), during the COVID-19 pandemic.MethodsAll women delivering in all the maternity centres of the canton of Geneva from 1st November 2020 to 30th November 2020 (beginning of the flu vaccination season) and from 8th March 2021 to 7th April 2021 (end of the flu vaccination season) had their records checked upon admission to the labour ward regarding pertussis and influenza vaccination during pregnancy. Reasons for non-vaccination were recorded. Univariate and multivariate analyses were done to identify predictors of vaccine uptake.Results951 women delivered in Geneva during the two study periods, of which 950 were included in the study. 86.2% were vaccinated against pertussis, with no significant difference between the study periods (87.5% vs 85% at the beginning and end of the flu vaccination season respectively). 49.8% were vaccinated against influenza, with no significant difference between the study periods (48.8% vs 50.7% beginning and end of the flu vaccination season respectively). The influenza vaccine was 5 times more likely not to be proposed (8.9% vs. 1.7%) and 3 times more likely to be refused (26.6% vs. 8%) than the pertussis vaccine. Main reason for refusal was a lack of maternal desire for both vaccines, but not vaccine fear. Maternal parity ≥ 1 was significantly associated with pertussis vaccine uptake at univariate analysis. Women were significantly more likely to accept the influenza vaccine if they had a university degree or if they did not deliver in a midwife-only run delivery unit in both univariate and multivariate analysis.ConclusionsIn Geneva, most gynaecologists offer pertussis immunization during antenatal care and uptake is high, but more efforts must be done to increase influenza vaccination coverage. Education level impacts maternal flu vaccination uptake, but other social disparities did not. |
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| Keywords: | Pertussis Influenza Flu Vaccine Pregnancy |
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