成人体重指数和总体脂肪与血脂异常的相关性

目的观察成人体重指数(BMI)、总体脂肪率及分布与血脂异常的相关性。方法对2006年1月至2007年4月在北京协和医院接受年度查体的302例健康成人进行横断面调查,采用多频生物电阻抗测定体重(BW)、总体脂肪(TBF)、腹部脂肪(AF)、内脏脂肪(VF)、内脏脂肪面积(VFA)和腰臀围比值(WHR),同时测定血清甘油三酯(TG)、总胆固醇(CHO)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C),分析BMI、TBF及分布与血脂异常的相关性。结果男性BMI肥胖和超重的发生率、WHR异常和血脂异常的发生率均显著高于女性(P<0.05),但女性表现为TBF%显著增高(P<0.05)。超重和肥胖组的TBF、WHR、AF、VF、VFA、CHO、TG和LDL-C均显著高于体重正常组(P<0.05)。血脂正常组,女性BMI和TBF与CHO、TG和LDL-C呈正相关(P<0.05),与HDL-C呈负相关(P<0.05)。血脂异常组,男性和女性均表现为BMI和TBF与TG呈正相关(P<0.05),男性BMI和TBF与TG和HDL-C呈负相关(P<0.05)。结论肥胖/超重和体脂总量超标可增加成年男性和女性血脂异常的发生风险。

Relationship between Body Mass Index, Total Body Fat, and Dyslipidemia

Objective To investigate the relationship between body mass index(BMI),total body fat(TBF),body fat distribution and dyslipidemia in adults.Methods A cross-sectional study was conducted in 302 healthy subjects who had yearly examination at PUMC Hospital from Jan.2006 to Apr.2007.Body weight(BW),TBF,abdomen fat(AF),visceral fat(VF),visceral fat area(VFA)and waist-to-hip ratio(WHR)were measured by multi-frequency bioelectric impedance analysis.Serum triglyceride(TG),total cholesterol(CHO),HDL-C and LDL-C were measured at the same time.Results The incidence of obesity/overweight,abnormal WHR and dyslipidemia in male was more higher than that in female(P<0.05)and the significant increase of TBF% in female was observed.TBF,WHR,AF,VF,VFA,CHO,TG,and LDL-C in obesity/overweight group were more higher than those in normal weight group(P<0.05).In normal lipid females,BMI and TBF showed significant positive or negative correlation with CHO,TG,and LDL(P<0.05)or HDL(P<0.05)respectively.In dyslipidemia group,the positive correlation between BMI and TBF was observed in both of males and females(P<0.05).And the negative correlation between BMI and TBF was observed in males(P<0.05).Conclusion Obesity/overweight and hyper-TBF increased the risk of dyslipidemia significantly both in male and female adults.