宁波市2002-2011年妇女子宫颈癌死亡情况及变化趋势

目的了解浙江省宁波市妇女子宫颈癌死亡特征及变化趋势。方法参照Arbyn等介绍的方法对宁波市2002-2011年上报的子宫颈癌死亡率进行校正,计算子宫颈癌粗死亡率。采用对数线性回归方法和加权χ2方法分析子宫颈癌死亡率的时间趋势和城乡妇女子宫颈癌死亡率的差异。结果 2002-2011年宁波市妇女子宫颈癌校正前粗死亡率为2.78/10万,中标率为2.18/10万,世标率为2.26/10万,校正后粗死亡率为5.19/10万,中标率为4.07/10万,世标率为4.21/10万。校正前后子宫颈癌死亡率均随年龄增长而升高（校正前χ2趋势=818.261,P=0.000;校正后χ2趋势=1 563.041,P=0.000）。2002-2011年宁波市妇女校正后子宫颈癌粗死亡率波动在4.41/10万～5.99/10万之间,差异无统计学意义（EAPC：0.60%,95%CI：-0.30%,1.51%）;中标率波动在3.52/10万～4.60/10万之间,有下降趋势（EAPC：-2.08%,95%CI：-3.63%,-0.40%）;世标率波动在3.51/10万～4.85/10万之间,有下降趋势（EAPC：-1.09%,95%CI：-1.88%,-0.20%）。农村妇女子宫颈癌死亡率高于城市妇女子宫颈癌死亡率（加权χ2=34.892,P=0.000）。结论随着时间的推移,宁波市妇女子宫颈癌呈下降趋势,但仍维持在较高水平,农村妇女子宫颈癌死亡率高于城市妇女子宫颈癌死亡率。

The dynamic change in mortality of women with cervical cancer in Ningbo of Zhejiang during 2002-2011

Objective To understand the characteristics of cervical cancer mortality and it＇s dynamic change from 2002 to 2011 in Ningbo. Methods The method which Marc Arbyn described was used to correct the mortality rates of cervical cancer. The crude death rate （CR） was calculated. The log-linear regression and weighted X2 were used to analyze the time trends of cervical mortality rate and the difference between women from urban and rural areas. Results Before and after the correction, the CR, CASR and WSR were 2.78/ lakh, 2.18/lakh, 2.26/ lakh and 5.19/ lakh, 4.07/lakh, 4.21/lakh, respectively. The mortality rates of cervical cancer increased with age regardless the correction （uncorrected X2trends 818. 261, P= 0. 000; correc ted x2trends 1563. 041, P=0. 000）. The corrected CR fluctuated between 4.41/lakh and 5.99/lakh during 2002 --2011 with no significant difference （EAPC： 0.60%, 95% CI： -0.30%, 1.51%, the corrected CASR fluctuated between 3.52/lakh -4.60/lakh with a downward trend （EAPC： -2.08%, 95% CI： -3.63%, - 0.40%） and the corrected WSR fluctuated between 3.51/lakh 4.85/lakh with a declined trend （EAPC： 1.09 %, 95 % CI： -1.88 %, 0.20 %） . Women in rural area had significantly higher mortality rate of cervicalcancer than their urban counterparts （weighted x2=34. 892, P= 0. 000）. Conclusions The mortality rate of cervical cancer shows a significantly decreasing trend during 2002-2011 in Ningbo, but is still in a high level and more women in rural areas die from cervical cancer than those in urban areas.