德谷胰岛素与甘精胰岛素治疗口服降糖药血糖控制不佳2型糖尿病患者的效果比较

目的 比较德谷胰岛素和甘精胰岛素治疗口服降糖药血糖控制不佳2型糖尿病患者的效果.方法 收集2020年6月—2021年6月盘锦市中医医院收治的口服降糖药血糖控制不佳2型糖尿病患者160例,随机分为对照组和观察组各80例,对照组采用甘精胰岛素联合门冬胰岛素治疗,观察组采用德谷胰岛素联合门冬胰岛素治疗.比较两组的血糖控制效果...

Effect of Insulin Degludec versus Insulin Glargine on Treatment of Type 2 Diabetes Mellitus Patients with Poor Blood Glucose Controlled by Oral Administration of Hypoglycemic Agents

Objective To compare the efficacy of insulin degludec and insulin glargine in the treatment of type 2 diabetes mellitus(T2DM) with poor blood glucose controlled by oral administration of hypoglycemic agents.Methods A total of 160 T2DM patients with poor blood glucose controlled by oral administration of hypoglycemic agents treated in Panjin Traditional Chinese Medicine Hospital from June 2020 to June 2021 were collected. The patients were randomly divided into control group and observation group with 80 cases in each group. The control group was treated with insulin glargine combined with insulin aspart. The observation group was treated with insulin degludec combined with insulin aspart. The blood glucose control and hypoglycemia occurrence were compared between the two groups. Results There was significant difference in fasting blood glucose and daily blood glucose standard time between the two groups(P < 0.05). There was significant difference in the frequency of nocturnal and severe hypoglycemia occurrence between the two groups(P < 0.05). Conclusion Compared with insulin glargine,insulin degludec has more stable effect on fasting blood glucose control, and fewer nocturnal hypoglycemia and severe hypoglycemia.