| 维生素D与儿童感染性疾病相关性及其抗感染机制研究 |
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| 引用本文： | 吴依然,张敏,崔明明,张文平.维生素D与儿童感染性疾病相关性及其抗感染机制研究[J].中国感染控制杂志,2020,19(11):1037-1041. |
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| 作者姓名： | 吴依然 张敏 崔明明 张文平 |
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| 作者单位： | 1. 首都儿科研究所儿童发育营养组学北京市重点实验室, 北京 100020;2. 山西医科大学公共卫生学院, 山西 太原 030009 |
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| 基金项目： | 北京市医院管理局市属医院科研培育计划（PX2019051） |
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| 摘 要： | 维生素D是类固醇类激素超家族中的一员，除调节钙磷代谢，维持儿童骨骼健康的经典作用外，维生素D还具有重要的免疫调节作用。近年来多项研究表明，维生素D低水平与儿童多种感染性疾病的发生、进展相关，维生素D增补被用于治疗与预防多种儿童感染性疾病。本文就维生素D营养状况与儿童感染性疾病的相关性及其抗感染机制进行简要综述。
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| 关 键 词： | 维生素D|感染性疾病|免疫系统|儿童 |
| 收稿时间： | 2020/1/13 0:00:00 |
Correlation between vitamin D and infectious diseases in children and its anti-infection mechanism |
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| WU Yi-ran,ZHANG Min,CUI Ming-ming,ZHANG Wen-ping.Correlation between vitamin D and infectious diseases in children and its anti-infection mechanism[J].Chinese Journal of Infection Control,2020,19(11):1037-1041. |
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| Authors: | WU Yi-ran ZHANG Min CUI Ming-ming ZHANG Wen-ping |
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| Institution: | 1. Beijing Key Laboratory of Child Development Nutrition, Capital Institute of Pediatrics, Beijing 100020, China;2. Department of Public Health, Shanxi Medical University, Taiyuan 030009, China |
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| Abstract: | Vitamin D is a member of steroid hormone superfamily, in addition to its'' classical function, such as regulating calcium and phosphorus metabolism as well as maintaining children''s bone health,vitamin D also plays an important role in immune regulation. In recent years, a number of studies have shown that low level of vitamin D is associated with the occurrence and progress of various infectious diseases in children, vitamin D supplementation is used to treat and prevent a variety of infectious diseases in children. In this paper, the relationship between vitamin D nutritional status and infectious diseases in children as well as its anti-infection mechanism are briefly reviewed. |
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| Keywords: | vitamin D|infectious disease|immune system|children |
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