| 鼠疫噬菌体研究概述 |
| |
| 引用本文： | 王梅.鼠疫噬菌体研究概述[J].中国媒介生物学及控制杂志,2011,22(3):297-300. |
| |
| 作者姓名： | 王梅 |
| |
| 作者单位： | 中国疾病预防控制中心传染病预防控制所鼠疫室,传染病预防控制国家重点实验室,北京,102206;青海省地方病预防控制所,西宁,811602 |
| |
| 摘 要： | 鼠疫噬菌体是一种特异性很强的鼠疫耶尔森菌（Yersinia pestis,鼠疫菌）的细菌病毒,一直被用来进行鼠疫病原体的鉴定。鼠疫噬菌体的早期研究主要以如何在自然界分离、生物学特性、诊断和治疗鼠疫,近年来,随着微生物基因组和蛋白质组学技术的发展,揭示了鼠疫噬菌体在鼠疫菌进化过程中所发生的作用。现就鼠疫噬菌体的研究进展,尤其是基因组的结构、与宿主菌在致病和免疫相关研究做一些介绍,为研发新型分子生物学技术和鼠疫治疗药物提供帮助。
|
| 关 键 词： | 鼠疫噬菌体 基因组 鼠疫 |
Overview of research on Yersinia pestis bacteriophage |
| |
| WANG Mei.Overview of research on Yersinia pestis bacteriophage[J].Chinese Journal of Vector Biology and Control,2011,22(3):297-300. |
| |
| Authors: | WANG Mei |
| |
| Institution: | WANG Mei1,2,HAI Rong1 1 State Key Laboratory for Infectious Disease Prevention and Control,National Institute for Communicable Disease Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 102206,China,2 Qinghai Institute for Endemic Disease Control and Prevention,Xining 811602,Qinghai Province |
| |
| Abstract: | Yersinia pestis bacteriophage,a strongly specific bacterial virus,is commonly used for identification of the plague pathogen. Early research on this bacteriophage has focused mainly on the natural isolation,biological characteristics,and diagnostic or therapeutic applications. In recent years,advances in microbial genomics and proteomics have shed light on the role of this bacteriophage in the evolution of Y. pestis. This paper summarizes recent progress in Y. pestis bacteriophage research regarding genome ... |
| |
| Keywords: | Yersinia pestis bacteriophage Genome Plague |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
