中国青少年1990与2019年HIV/AIDS疾病负担性别差异

  目的  分析1990年与2019年中国10~24岁青少年人群HIV/AIDS疾病负担在性别中的变化，为制定针对该年龄层人群的有效干预措施提供信息。  方法  使用全球疾病负担(Global Burden of Disease，GBD)2019数据库资料，按性别和年龄提取1990—2019年中国10~24岁青少年人群因HIV/AIDS的死亡数和死亡率、伤残调整寿命年(DALY)、DALY率、过早死亡损失寿命年(YLL)、YLL率、伤残损失寿命年(YLD)、YLD率等指标来分析该群体HIV/AIDS疾病负担在性别中的变化幅度。  结果  2019年，中国10~24岁青少年人群因HIV/AIDS的死亡数和死亡率、DALY、DALY率、YLL、YLL率、YLD与YLD率分别为847人、0.37/10万、62 621人年、27.51/10万、58 036人年、25.49/10万、4 584人年与2.01/10万，相比1990年增幅分别为401.18%，691.49%，370.48%，648.26%，409.53%，710.33%，138.87%与279.25%。2019年中国10~14，15~19岁与20~24岁男性因HIV/AIDS的死亡数和死亡率、DALY与DALY率均高于女性，与1990年相比，增幅均高于女性；10~14岁人群疾病负担增幅高于20~24岁。1990—2019年，随着年龄和年份的增加，青少年死亡率和DALY率的性别差距增大。  结论  与1990年相比，2019年中国10~24岁青少年人群HIV/AIDS感染风险持续增加，低龄HIV感染者增幅明显，性别差异日益明显。

Gender disparities in epidemiological trend of HIV/AIDS disease burden among Chinese adolescents from 1990 to 2019

  Objective  To analysis gender disparities in epidemiological trend of HIV/AIDS disease burden among Chinese population aged 10-24 years from 1990 to 2019.  Methods  The Global Burden of Disease Study (GBD 2019) results tool was used to extract the number of deaths, mortality rate, disability adjusted life years (DALY), DALY rate, years of life lost (YLL), YLL rate, years lived with disability (YLD) and YLD rate to comprehensively analyze the change range of HIV/AIDS disease burden in the Chinese population aged 10-24 years from 1990 to 2019.  Results  In 2019, the number of deaths, mortality rate, DALY, DALY rate, YLL, YLL rate, YLD and YLD rate of Chinese population aged 10-24 years due to HIV/AIDS were 847, 0.37 per 100 000, 62 621 person years, 27.51 per 100 000, 58 036 person years, 25.49 per 100 000, 4 584 person years, 2.01 per 100 000 respectively, with the increase of 401.18%, 691.49%, 370.48%, 648.26%, 409.53%, 710.33%, 138.87% and 279.25%, compared with the data in 1990. In term of gender, the number of deaths, mortality rate, DALY, and DALY rate of Chinese male population aged 10-14, 15-19 and 20-24 years due to HIV/AIDS in 2019 were higher than those of female, and the growth rate (compared with 1990) was also higher than that of female. In term of the age group, the increase in people aged 10-14 years was higher than that of people aged 20-24 years. From 1990 to 2019, with the increase of year and age, gender disparity between mortality and DALY rate widened.  Conclusions  Compared with data in 1990, the risk of HIV/AIDS infection in 2019 among Chinese population aged 10-24 years continued to increase, especially among young people of 10-14 years. Gender disparity is exacerbating.