2017年泰州市重点职业病危害因素接触人员职业健康风险评估分析

依据《江苏省重点职业病监测与职业健康风险评估工作实施方案》要求，分析泰州市职业健康检查、职业病诊断与鉴定、职业病患者工伤保险待遇落实及职业病报告信息。结果显示，2017年职业健康检查共16759人，检出职业病10例，疑似职业病23例，职业禁忌证22人。职业病患者均已享受工伤保险待遇。泰州市重点职业病危害因素为电焊烟尘、矽尘和噪声，应进一步加强职业健康监护工作。

Assessment and analysis on occupational health risk of workers exposed to key occupational hazards in Taizhou city in 2017

The establishment of animal models of highly pathogenic coronavirus is of great significance to the research of vaccine, antibody, drugs and viral pathogenic mechanism. Non-human primates, ferrets, Syrian hamsters have been applied to establish animal models of coronavirus infection and disease, different animal models may simulate and reproduce clinical infection symptoms in various aspects. However, from the perspective of applicability, economy and easy access, establishing a mouse model susceptible for coronavirus and supplying sufficient animals rapidly exert more practical significance on the prevention and control of coronavirus outbreak. This paper briefly de scribes the advances of animal models for 3 highly pathogenic coronavirus, including MERS-CoV, SARS-CoV and 2019 novel coronavirus (2019-nCoV). Based on the new publication on Nature, demonstrating that SARS-CoV and 2019-nCoV may share the human ACE2 receptor to infect the host, we speculate that the hACE2-KI/NIFDC humanized mouse model constructed by us in 2018 is expected to be a susceptible mouse model for 2019-nCoV.