绿茶提取物对体外培养的人体胃腺癌细胞的作用

Effect of Chinese green tea extracts on the human gastric carcinoma cell in vitro

We have studied and found antitumor effects in Chinese green tea extracts (T-8750). By pharmacologic test, it showed anticancer actions against several kinds of tumors in NIH mice evidently. Clinical trials on the therapeutics effects against early stomach cancer showed very effective. In order to prove it's function to prevent cancer. The research results as follows: (1) In vitro, T-8750 (0.5-1 mg/ml) could inhibit the cell growth of SGC (stomach gastric cancer) significantly. The inhibition action are obviously within 12-24 hr. (2) T-8750 traversed the migration of cell line L1210 from G1 phase to S phase, the rate were (63%). (3) In vitro, the blocking effect of T-8750 on the nitrosation of morpholine-nitrite was (92.4%). (4) the effect of T-8750 scavenger harmful free radicals was (63%).