饮用绿茶对胃癌、肝癌和食管癌预防作用研究

目的 探讨饮绿茶对3种上消化系统癌症(胃癌、肝癌、食管癌)的预防作用。方法 选择江苏省泰兴市的胃癌、肝癌、食管癌病例分别为206、204、218例及对照415例。结果 饮用绿茶可降低饮用者胃癌危险度40％，调整可能的混杂因素后OR值为0．60(95％CI：0．36—0．99)，并且随饮绿茶年限增长、浓度增高和饮用量的增加，保护作用增强，呈明显的剂量-效应关系。当每月饮茶超过250g时，对肝癌的保护效率约可达60％。饮绿茶对肝癌可能有一定的保护作用趋势，但统计学检验不显著，而饮绿茶对患食管癌无明显影响。结论 饮绿茶对胃癌可能具有一定的保护作用，而对食管癌、肝癌未见明显保护作用。

Study on the protective effect of green tea on gastric,liver and esophageal cancers

Objective To assess the protective effect of drinking green tea on the development of gastric,liver and esophageal cancers. Methods A population based study was conducted in Taixing,Jiangsu province,including 206,204,218 cases,respectively,and 415 population controls. Results Green tea decreased the development of gastric cancer risk by 40%.Dose-response relationships were observed between the length of time,concentration and quantity of green tea drinking and its protective effects on gastric cancer.For individuals who drink green tea for more than 250 g per month,the risk of gastric cancer reduced about 60%.Green tea might have protective effect on liver cancer.However,no protective effect of green tea was observed on esophageal cancer. Conclusion Green tea drinking might be a protective factor for gastric cancer.However,the protective effects of green tea on liver and esophageal cancer were not obvious.