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对居民使用液化气健康效应的初步探讨
引用本文:高泽宣,唐明德.对居民使用液化气健康效应的初步探讨[J].中华预防医学杂志,1994,28(3):154-157.
作者姓名:高泽宣  唐明德
作者单位:湖南医科大学环境卫生学教研室
摘    要:对液化气燃烧后室内空气污染进行了流行病学调查,结果显示,液化气燃烧可造成SO_2、NO_2、空气总悬浮颗粒物和总烃类的室内空气污染。小鼠接触三个月出现T淋巴细胞计数降低、睡眠时间延长、骨髓嗜多染红细胞微核率增加、肺组织匀浆Ames试验阳性率增高、雄性小鼠精子畸形率增加,并有明显的剂量-反应关系。对接触5年以上的人群调查发现,呼吸道、鼻和眼的自觉症状明显增加,咽炎、鼻炎、结膜炎患病率增高。人群尿液浓缩物Ames试验和外周血红细胞微核率检出阳性结果,可能与液化气燃烧废气中含有致突变污染物有关。

关 键 词:空气污染,毒理学

Preliminary Study on Health Effects in the Residents Exposed to Liquefied Petroleum Gas
Gao Ze-xuan,Tang Ming-de,Yi Yi-zhen,et al..Preliminary Study on Health Effects in the Residents Exposed to Liquefied Petroleum Gas[J].Chinese Journal of Preventive Medicine,1994,28(3):154-157.
Authors:Gao Ze-xuan  Tang Ming-de  Yi Yi-zhen  
Institution:Gao Ze-xuan,Tang Ming-de,Yi Yi-zhen,et al.Department of Environment Health Hunan Medical Univer-sity,Changsha,410078
Abstract:ombustion of liquefied petroleum gas(LPG)can cause indoor air pollution with sulfur dioxide,nitrogen dioxide,total suspended particulate(TSP)and total hydrocarbons.Mice exposed to the pollutant air for three mouths showed lower ANAE,prolonged sleep time,increased PCE micronucleus in bone marrow, high positivity in Ames test for the lung homogenate and deformity of sperm in males,with obvious dose-response relationship.Investigation on a human population exposed to LPG for more than five years revealed irritating symptoms in respiratory tract,nose and eyes,and prevalence of pharyngitis,rhinitis and conjunctivitis increased significantly.Positive Ames test and micronucleus test in peripheral erythrocytes were detected in concentrated urine samples collected from them. It is postu-lated this may be associated with the mutagenic pollutants contained in the waste gas emitted by com-bustion of LPG.
Keywords:Air pollution  Toxicology
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