| 清热片成型工艺改进研究 |
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| 引用本文： | 王怀豫,易延逵. 清热片成型工艺改进研究[J]. 医疗保健器具, 2011, 18(10): 1525-1527. DOI: 10.3969/j.issn.1674-4659.2011.10.1525 |
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| 作者姓名： | 王怀豫 易延逵 |
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| 作者单位： | 1. 无限极(中国)有限公司,广东,广州,510665
2. 南方医科大学,广东,广州,510515 |
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| 摘 要： | 目的解决清热片生产过程中存在的裂片、脆碎度不合格等问题。方法采用单因素试验,以口感、压片情况、硬度、崩解度等为考查指标,考查了羧甲基纤维素钠用量、酒精浓度、糊精与淀粉配比、粘合剂种类等。结果羧甲基纤维素钠用量控制在2%为宜;乙醇浓度采用60%比较理想;糊精与淀粉配比控制在13∶5为宜;糊精、淀粉和羧甲基纤维素钠比例以13∶5∶2为好。结论本试验为清热片成型工艺改进提供了依据。
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| 关 键 词： | 清热片 裂片 成型工艺 |
Study on improving the Forming Technology of Qingre Tablets |
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| WANG Huaiyu,YI Yankui. Study on improving the Forming Technology of Qingre Tablets[J]. Medicine Healthcare Apparatus, 2011, 18(10): 1525-1527. DOI: 10.3969/j.issn.1674-4659.2011.10.1525 |
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| Authors: | WANG Huaiyu YI Yankui |
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| Affiliation: | WANG Huaiyu 1,YI Yankui 2* (1Infinitus(China)Co.,LTD,Guangzhou 510665,China,2Southern Medical University,Guangzhou 510515,China) |
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| Abstract: | Objective To solve the problems of sliver and friability disqualification of Qingre tablets. Methods To deploy mono-factor, to take mouth responding, tabletting information, hardness, disintegration grade as the reviewing index, and to review the dosage of CMC-Na, alcohol density, the matching of dextrin and starch, and adhesive material variety, etc. Results Dosage of CMC-Na control which was about 2% was appropriate, alcohol density adopting 60% was ideal, the matching of dextrin and starch control was ab... |
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| Keywords: | Qingre tablets Sliver Forming technology |
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