首页 | 本学科首页   官方微博 | 高级检索  
检索        

MRSA呼吸系统医院感染的分子流行病学调查
引用本文:吴礼襄,萧正伦,黎毅敏.MRSA呼吸系统医院感染的分子流行病学调查[J].中华医院感染学杂志,2004,14(4):453-457.
作者姓名:吴礼襄  萧正伦  黎毅敏
作者单位:广州呼吸疾病研究所,广东,广州,510120
摘    要:目的对广州呼吸疾病研究所2001年7月~2003年3月间,金黄色葡萄球菌引起的呼吸系统医院感染进行病原学监测. 方法收集临床分离菌株,应用脉冲场凝胶电泳的方法(PFGE)进行分型,确定菌株亲缘关系,结合临床资料分析. 结果在各种呼吸道采集标本中共收集到76株金黄色葡萄球菌,耐甲氧西林金黄色葡萄球菌(MRSA)68株,占金黄色葡萄球菌检出率89.47%,MRSA在我所病区中引起59例医院感染,属于暴发形式发病的有23例,属于聚集性发病的有19例,散发病例17例,PFGE分型表明,绝大多数MRSA属于同一型(A型)共有60株,其中A1亚型28株,A2亚型14株,A3亚型17株,A4亚型1株. 结论MRSA引起的呼吸系统医院感染十分严重,并主要由少数菌株的传播引起,及时采取有效措施控制MRSA的流行和播散非常必要.

关 键 词:金黄色葡萄球菌  甲氧西林耐药  暴发流行  医院感染  脉冲场凝胶电泳  基因分型
文章编号:1005-4529(2004)04-0453-05
修稿时间:2003年9月10日

Meticillin-resistant Staphylococcus aureus in A Respiratory Disease Institute:An Epidemiologic Survey by PFGE
WU Li-xiang,XIAO Zheng-lun,LI Yi-min.Meticillin-resistant Staphylococcus aureus in A Respiratory Disease Institute:An Epidemiologic Survey by PFGE[J].Chinese Journal of Nosocomiology,2004,14(4):453-457.
Authors:WU Li-xiang  XIAO Zheng-lun  LI Yi-min
Abstract:OBJECTIVE To investigate the outbreak of MRSA in respiratory ward. METHODS Seventy-six Staphylococcus aureus strains isolated in the respiratory ward of Guangzhou Medical College Hospital between Jul 2001 and Mar 2003 were studied. All the MRSA were identified by using commonly phenotypic procedure combined with MRSA screen latex test and on all isolates susceptibility tests were performed. Genotypes of the isolates were investigated by pulsed-field gel electrophoresis (PFGE). RESULTS There were 68 MRSA isolates among 76 S. aureus isolates (89.47%). Fifty nine strains of them were nosocomial infection pathogens. Outbreaks were registered to 23 cases and cluster 19, while single events remained 28.81% of all MRSA infections. The PFGE patterns of 68 MRSA isolates were classified into 10 types and subtypes, from them: type A (a total of 60 isolates) and its subtypes A1(28) and A2(14), A3(17), A4(1) were predominant. CONCLUSIONS The respiratory nosocomial infection caused by MRSA is serious. It is necessary to take effective measures to control the MRSA prevalence.
Keywords:Staphylococcus aureus  Meticillin-resistance  Outbreak  Nosocomial infection  Pulsed-field gel electrophoresis
本文献已被 CNKI 维普 万方数据 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号