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心脏外科监护病房革兰阴性杆菌感染监测
引用本文:贾明,邵涓涓,陈菲,李菲,陈英,杨毅,贺建勋,李京明,贾士杰.心脏外科监护病房革兰阴性杆菌感染监测[J].中华医院感染学杂志,2007,17(8):936-938.
作者姓名:贾明  邵涓涓  陈菲  李菲  陈英  杨毅  贺建勋  李京明  贾士杰
作者单位:首都医科大学附属北京安贞医院,北京,100029
摘    要:目的了解医院心脏外科重症监护病房(ICU)革兰阴性杆菌感染情况。方法回顾医院ICU2000年1月--2005年12月,感染患者各种标本分离到的革兰阴性杆菌的药敏结果。结果共分离出革兰阴性杆菌349株,大多数感染源于呼吸道(308株,88%),前4位革兰阴性致病菌为不动杆菌属、铜绿假单胞菌、肺炎克雷伯菌、嗜麦芽寡养单胞菌,药敏结果显示碳青酶烯类抗菌药物、头孢哌酮/舒巴坦、头孢吡肟保持较高抗菌活性。结论医院ICU革兰阴性致病菌呈现多重耐药,嗜麦芽寡养单胞菌以及ESBLs阳性的肺炎克雷伯菌感染不容忽视。

关 键 词:心脏外科监护病房  革兰阴性杆菌  感染  耐药性
文章编号:1005-4529(2007)08-0936-03
收稿时间:2006-08-25
修稿时间:2006-08-252006-11-20

Monitoring of Gram-negative Bacilli in Intensive Care Unit of Cardiac Surgery
JIA Ming,SHAO Juan-juan,CHEN Fei,LI Fei,CHEN Ying,YANG Yi,HE Jian-xun,LI Jing-ming,JIA Shi-jie.Monitoring of Gram-negative Bacilli in Intensive Care Unit of Cardiac Surgery[J].Chinese Journal of Nosocomiology,2007,17(8):936-938.
Authors:JIA Ming  SHAO Juan-juan  CHEN Fei  LI Fei  CHEN Ying  YANG Yi  HE Jian-xun  LI Jing-ming  JIA Shi-jie
Institution:Anzhen Hospital Affiliated to Capital University of Medical Sciences, Beijing 100029, China
Abstract:OBJECTIVE To investigate the distribution and antibiotics resistance of Gram-negative bacilli in intensive care unit(ICU) of cardiac surgery,and direct clinical medication.METHODS The antimicrobial susceptibility of clinical isolates from infected patients on the ICU from Jan 2000 to Dec 2005 were analyzed retrospectively.RESULTS There were 349 clinical isolates of Gram-negative bacilli,and 308(88%) of them were isolated from sputum while 41(12%) from blood.Acinetobacter spp,Pseudomonas aeruginosa,Klebsiella pneumoniae and Stenotrophomonas maltophilia were the predominant ones(268 strains,76.8%).Results of susceptibility test showed that carbopenems,cefoperazone-sulbactam and cefepime were the most active antibiotics.CONCLUSIONS The Gram-negative pathogenic bacteria in our department present multidrug resistance.The infection of S.maltophilia and ESBLs-producing K.pneumoniae is increasing,we must pay attention to them.
Keywords:Intensive care unit of cardiac surgery  Gram-negative bacilli  Infection  Antibiotics resistance
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