| 胸外科手术预防性应用抗生素的临床研究 |
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| 引用本文： | 陈刚,肖朴,花柱明,崔建修.胸外科手术预防性应用抗生素的临床研究[J].中华医院感染学杂志,2003,13(3):266-268. |
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| 作者姓名： | 陈刚 肖朴 花柱明 崔建修 |
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| 作者单位： | 广东省人民医院,广东,广州,510080 |
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| 摘 要： | 目的：探讨预防性合理应用抗生素对胸外科手术后感染的医学和经验学效益，方法：采用前瞻性随机对照研究，对比以观察268例胸外科患者围术期不同给药方法的临床和经济学效果。结果：实验组和常规用药组相比较，其预防术后感染的效果差别无显著性，平均住院时间，术后平均住院时间等差别亦无明显性，而住院总费用及抗生素费用等则明显低于常规用药组。结论：围术期应用双剂头孢西丁预测胸外科相后感染是一种合理有效而经济的预防方案。
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| 关 键 词： | 胸外科手术 预防性抗生素 围术期 感染 |
| 文章编号： | 1005-4529(2003)03-0266-03 |
| 修稿时间： | 2002年7月10日 |
Antibiotic Prophylaxis in Thoracic Operation:A Clinical Research |
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| CHEN Gang,XIAO Pu,HUA Zhu ming,CUI Jian xiu.Antibiotic Prophylaxis in Thoracic Operation:A Clinical Research[J].Chinese Journal of Nosocomiology,2003,13(3):266-268. |
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| Authors: | CHEN Gang XIAO Pu HUA Zhu ming CUI Jian xiu |
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| Abstract: | OBJECTIVE To discuss medical and economic efficiency of rational antibiotic prophylaxis in patients receiving thoracic operations. METHODS In a prospective study of 268 thoracic surgical patients with different drug administration in perioperative period, clinical and economic efficiency is compared. RESULTS There is no significant difference between the experimental group and the control one either in prevention of postoperative infection or in the mean hospital stay or the mean postoperative hospital stay. Otherwise the total cost of hospitalization and antibiotics of the experimental group is much less than that of the control one. CONCLUSIONS Application of two dosages of cefoxitin in perioperative period is a rational effective and economic prophylactic regime to prevent thoracic surgical patients from postoperative infection. |
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| Keywords: | Thoracic operation Antibiotic prophylaxis Perioperative period Infection |
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