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替考拉宁治疗老年患者MRSA肺部感染21例疗效观察
引用本文:高景,邢丽华,高炜,李振华,王宁,焦婧.替考拉宁治疗老年患者MRSA肺部感染21例疗效观察[J].中华医院感染学杂志,2010,20(5).
作者姓名:高景  邢丽华  高炜  李振华  王宁  焦婧
作者单位:郑州大学第一附属医院呼吸内科,河南,郑州,450052
摘    要:目的 评价替考拉宁治疗耐甲氧西林金黄色葡萄球菌(MRSA)肺部感染的老年患者临床疗效和安全性.方法 对21例耐甲氧西林金黄色葡萄球菌肺部感染老年患者给予替考拉宁针,第1天400 mg静脉滴注,第2天以后每日200 mg静脉滴注,连用10~14 d治疗,比较治疗前后患者的临床症状、体征、实验室检查及细菌学结果 ,并判定疗效.结果 替考拉宁治疗老年患者MRSA肺部感染临床有效率为81.0%,细菌清除率为85.7%,不良反应发生率为9.5%,不良反应发生率低.结论 合理利用替考拉宁治疗老年患者MRSA肺部感染疗效高,安全有效.

关 键 词:替考拉宁  老年患者  耐甲氧西林金黄色葡萄球菌  肺部感染

Glycopeptides Antibiotics Teicoplanin in Elder Patients with Lung Infection due to MRSA:Evaluation of Efficacy and Safety
GAO Jing,XING Li-hua,GAO Wei,LI Zhen-hua,WANG Ning,JIAO Jing.Glycopeptides Antibiotics Teicoplanin in Elder Patients with Lung Infection due to MRSA:Evaluation of Efficacy and Safety[J].Chinese Journal of Nosocomiology,2010,20(5).
Authors:GAO Jing  XING Li-hua  GAO Wei  LI Zhen-hua  WANG Ning  JIAO Jing
Institution:GAO Jing,XING Li-hua,GAO Wei,LI Zhen-hua,WANG Ning,JIAO Jing(The First Affiliated Hospital,Zhengzhou University,Zhengzhou,Henan 450052,China)
Abstract:OBJECTIVE To evaluate efficacy and safety of glycopeptides antibiotics teicoplanin in elder patients with lung infection due to MRSA. METHODS Twenty-one elderly patients with lung infection due to meticillin-resistant Staphylococcus aereus (MRSA) were treated with teicoplanin 200mg,twice in the first day,then once a day in the following 10-14 days.The therapeutic effect,clearance rate of pathogens,and side effects were compared and evaluated before and after treatment. RESULTS The clinical effective rate of...
Keywords:Teicoplanin  Eider patients  MRSA  Lung infection
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