| 新生儿呼吸合胞病毒下呼吸道感染临床分析 |
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| 引用本文： | 程可萍,胡源,郎平,郭明华.新生儿呼吸合胞病毒下呼吸道感染临床分析[J].中华医院感染学杂志,2011(18):3823-3825. |
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| 作者姓名： | 程可萍 胡源 郎平 郭明华 |
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| 作者单位： | 永康市妇幼保健院新生儿科,浙江永康,321300 |
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| 摘 要： | 目的探讨新生儿呼吸合胞病毒下呼吸道感染的临床特点。方法选取2008年5月-2011年4月,在医院进行治疗的呼吸合胞病毒下呼吸道感染260例新生儿为研究对象,对其采用氧疗、雾化吸入及抗病毒、抗菌药物治疗,后将其治疗有效率、住院时间及治疗前后的血清IL-4、IL-6、IL-12、CRP、IgE及外周血T淋巴细胞亚群水平进行统计比较。结果 260例患儿痊愈239例,好转20例,无效1例,总有效率为99.62%,住院时间为(12.8±2.8)d,治疗后IL-4、IL-6、IL-12分别为(7.55±2.69)、(16.69±7.14)、(56.48±13.39)ng/L,CRP为(6.88±2.39)mg/L,CD8+为(26.52±5.69)%均高于治疗前;治疗后IgE为(808.34±205.30)μg/L,CD3+、CD4+分别为(63.12±5.20)%、(45.58±5.20)%,CD4+/CD8+为(1.68±0.43)%,均高于治疗前,治疗前后差异有统计学意义(P<0.05)。结论经合理治疗,新生儿呼吸合胞病毒下呼吸道感染治疗效果较佳,可显著改善炎性因子及免疫状态。
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| 关 键 词： | 新生儿 呼吸合胞病毒 下呼吸道感染 疗效 |
Clinical analysis of newborns with respiratory syncytial virus and lower respiratory tract infection |
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| CHENG Ke-ping,HU Yuan,LANG Ping,GUO Ming-hua.Clinical analysis of newborns with respiratory syncytial virus and lower respiratory tract infection[J].Chinese Journal of Nosocomiology,2011(18):3823-3825. |
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| Authors: | CHENG Ke-ping HU Yuan LANG Ping GUO Ming-hua |
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| Institution: | CHENG Ke-ping,HU Yuan,LANG Ping,GUO Ming-hua(Maternal and Child Heath Hospital of Yongkang City,Yongkang,Zhejiang 321300,China) |
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| Abstract: | OBJECTIVE To study the clinical characteristics of newborns with respiratory syncytial virus and lower respiratory tract infection.METHODS A total of 260 newborns with respiratory syncytial virus and lower respiratory tract infection in our hospital from May 2008 to Apr 2011 were selected as research object.The treatment effect of oxygen therapy,atomization,antiviral drugs and antibiotics,and the hospitalization time and serum IL-4,IL-6,IL-12,CRP,IgE and peripheral blood T lymphocyte subsets of patients bef... |
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| Keywords: | Newborns Respiratory syncytial virus Lower respiratory tract infection Curative effect |
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