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抗菌药物使用继发酵母样真菌感染的调查与耐药性分析
引用本文:刘旗明,刘旗军,叶瑞梅.抗菌药物使用继发酵母样真菌感染的调查与耐药性分析[J].中华医院感染学杂志,2010,20(19).
作者姓名:刘旗明  刘旗军  叶瑞梅
作者单位:1. 衢州市柯城区人民医院检验科,浙江,衙州,324000
2. 衙州市常山县人民医院妇产科,浙江,衢州,324200
摘    要:目的 调查抗菌药物继发院内真菌感染的情况,以减少继发真菌感染的发生.方法 对2007-2008年使用抗菌药的住院患者为试验组进行真菌培养,对照组为入院抗菌药物使用前的临床标本.结果 应用抗菌药物继发真菌感染达35.5%,占同期真菌感染的80.9%,白色假丝酵母菌为主要致病菌,占59.8%;感染部位以呼吸道最多;药敏试验结果,两性霉素B敏感率85.1%;酮康唑敏感率最低,为54.0%,其他药物耐药性也有所增加.结论 使用抗菌药物的住院患者酵母样真菌感染率高,与对照组比较有差异,出现了不同程度的耐药株,提示临床临床选用抗菌药物注意真菌继发感染,治疗真菌感染应以培养和药敏试验为依据.

关 键 词:抗菌药物  感染  酵母样真菌  药敏试验

Antibacterial Drugs-induced Yeast-like Fungal Infections:Investigation and Analysis of Drug Resistance
LIU Qi-ming,LIU Qi-jun,YE Rui-mei.Antibacterial Drugs-induced Yeast-like Fungal Infections:Investigation and Analysis of Drug Resistance[J].Chinese Journal of Nosocomiology,2010,20(19).
Authors:LIU Qi-ming  LIU Qi-jun  YE Rui-mei
Abstract:OBJECTIVE To investigate the antibacterial agents-induced nosocomial fungal infections,and to reduce the occurrence of secondary fungal infections.METHODS The clinical specimens collected from inpatients in 2007-2008 were divided into two groups:the test group was after antibacterials use and the control group was before antibacterials use and cultured for fungi.RESULTS The fungal infection rate in test group was up to 35.5%,accounting for 80.9% in the same period of fungal infection.Candida albicans were t...
Keywords:Antibacterial drugs  Infections  Yeast-like fungi  Susceptibility test  
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