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Pathologic Changes in Wild Birds Infected with Highly Pathogenic Avian Influenza A(H5N8) Viruses,South Korea, 2014
Authors:Hye-Ryoung Kim  Yong-Kuk Kwon  Il Jang  Youn-Jeong Lee  Hyun-Mi Kang  Eun-Kyoung Lee  Byung-Min Song  Hee-Soo Lee  Yi-Seok Joo  Kyung-Hyun Lee  Hyun-Kyoung Lee  Kang-Hyun Baek  You-Chan Bae
Institution:Animal and Plant Quarantine Agency, Anyang, South Korea
Abstract:In January 2014, an outbreak of infection with highly pathogenic avian influenza (HPAI) A(H5N8) virus began on a duck farm in South Korea and spread to other poultry farms nearby. During this outbreak, many sick or dead wild birds were found around habitats frequented by migratory birds. To determine the causes of death, we examined 771 wild bird carcasses and identified HPAI A(H5N8) virus in 167. Gross and histologic lesions were observed in pancreas, lung, brain, and kidney of Baikal teals, bean geese, and whooper swans but not mallard ducks. Such lesions are consistent with lethal HPAI A(H5N8) virus infection. However, some HPAI-positive birds had died of gunshot wounds, peritonitis, or agrochemical poisoning rather than virus infection. These findings suggest that susceptibility to HPAI A(H5N8) virus varies among species of migratory birds and that asymptomatic migratory birds could be carriers of this virus.
Keywords:highly pathogenic avian influenza  H5N8 subtype  migratory bird  pathological diagnosis  immunohistochemistry  South Korea  influenza  viruses  respiratory infections
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