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Global Avian Influenza Surveillance in Wild Birds: A Strategy to Capture Viral Diversity
Authors:Catherine C Machalaba  Sarah E Elwood  Simona Forcella  Kristine M Smith  Keith Hamilton  Karim B Jebara  David E Swayne  Richard J Webby  Elizabeth Mumford  Jonna AK Mazet  Nicolas Gaidet  Peter Daszak  William B Karesh
Abstract:Wild birds play a major role in the evolution, maintenance, and spread of avian influenza viruses. However, surveillance for these viruses in wild birds is sporadic, geographically biased, and often limited to the last outbreak virus. To identify opportunities to optimize wild bird surveillance for understanding viral diversity, we reviewed responses to a World Organisation for Animal Health–administered survey, government reports to this organization, articles on Web of Knowledge, and the Influenza Research Database. At least 119 countries conducted avian influenza virus surveillance in wild birds during 2008–2013, but coordination and standardization was lacking among surveillance efforts, and most focused on limited subsets of influenza viruses. Given high financial and public health burdens of recent avian influenza outbreaks, we call for sustained, cost-effective investments in locations with high avian influenza diversity in wild birds and efforts to promote standardized sampling, testing, and reporting methods, including full-genome sequencing and sharing of isolates with the scientific community.
Keywords:influenza  influenza virus  viruses  wild birds  global avian influenza surveillance  viral diversity  epidemiologic monitoring  molecular evolution  genetic variation  genomic library  animal diseases  zoonoses  genetic databases  disease reservoirs  Organisation for Animal Health  OIE  One Health
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