北京市东城区产科医院1999～2009年出生缺陷资料分析

目的:了解北京市东城区产科医院出生缺陷发生情况,为制定干预措施,降低出生缺陷发生率提供依据。方法:对近10年该区产科医院出生缺陷发生情况进行回顾性分析。结果:围产儿共113565例,死亡1134例,死亡率为9.99‰;出生缺陷1693例,发生率为14.91‰;由出生缺陷导致死亡403例,占围产儿死亡的35.54%。10年间平均出生缺陷产前检出率为28.98%。结论:应继续宣传围孕期服用叶酸的重要性,降低神经管畸形发生率;加强产前筛查及产前诊断工作,提高出生缺陷产前检出率,降低出生缺陷发生率。

Prevalence of birth defects between 1999 and 2009 in Dongcheng District of Beijing

Objective：To explore the prevalence of birth defects in the maternity hospitals of Dongcheng District of Beijing in order to provide a scientific basis for birth defect prevention.Methods：A retrospective analysis was conducted to evaluate the prevalence of birth defects between 1999 and 2009 in the maternity hospitals of Dongcheng District of Beijing.Results：The perinatal mortality was 9.99‰（1 134/113 565）.The incidence of birth defects was 14.91‰（1 693/113 565）.A total of 403 deaths for birth defects accounted for 35.54% of the prenatal mortality.An average of 28.98% of the birth defects could be detected by the prenatal examination.Conclusion：The importance of folic supplement should be further propagandized in order to reduce the occurrence of neural tube defects.Meanwhile,prenatal screening and diagnosis should be strengthened for birth defect prevention.