急性光气中毒的临床特点研究

目的：探讨急性光气中毒的临床特点。方法：采用本院近28年120例急性光气中毒的病例资料。重点对发病时间，临床所见，诊治结果进行综合分析。结果：急性光气中毒的潜伏期1．5h-3d，中，重度中毒组中，现场及时处理组的潜伏期较未及时处理组延长（P＜0．05），临床表现以呼吸系统症状体征为主，其中呼吸频速，发疳，泡沫痰主要发生在重度中毒组中的ARDS病例，心肌损害发生率各中毒组间比较，差异有显著性（P＜0．01），在轻度中毒组中，入院时X线胸片异常率显著高于肺部听诊阳性率（P＜0．01），结论：急性光气中毒时，若现场能得到及时处理，可使潜伏期延长，肺是靶器官，心肌损害发生率随着中毒程度的加重而增加，X线胸片改变往往早于临床体征，可作为早期重要检测手段之一。

STUDY ON CLINICAL FEATURES OF ACUTE PHOSGENE POISONING

Objective To explore the clinical features of acute phosgene poisoning.Methods By gathering 120 cases in our hospital for recent 28 years, the latency phase, clinical manifestation, results of diagnosis and treatment were analyzed syntheticly. Results The latency phase 1.5h to 3d. In the moderate and severe poisoning groups, the latency phase of the group which handled in time was longer than that of not in time(P<0.05). The main clinical manifestation was the sympton and sign of respiratory system. Breathing frequently, cyanosis, and frothy sputum existed in the ARDS cases of severe poisoning. The rate of heart damage in each poisoning group was obviously different(P<0.01). The rate of abnormal chest X-ray findings was evidently higher than that of abnormal pulmonary auscultation in mild poisoning group during admition(P<0.01). Conclusion When acute phosgene poisoning occured, the latency phase can be extended if the patients were handled in time. Lung was the target organ. The rate of heart damage was increased with the poisoning degree. The chest X-ray findings was always earlier than clinical signs, it may be one of the important primary checking ways.