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青岛市成人双生子体型指征的遗传度研究
引用本文:吴伟风,逄增昌,马爱国.青岛市成人双生子体型指征的遗传度研究[J].中国公共卫生,2005,21(4):413-415.
作者姓名:吴伟风  逄增昌  马爱国
作者单位:1. 青岛大学医学院营养研究所,266021
2. 青岛市疾病预防控制中心
基金项目:中华医学基金 (CMB)资助项目 (0 1 - 746)
摘    要:目的探讨遗传因素对体质指数(BMI)和腰臀围比值(WHR)等体型指征的影响程度。方法青岛地区自愿参加本研究的496对24周岁及以上的双生子。在卵型鉴定的基础上。应用Mx软件构建结构方程模型分析遗传度。结果估计体质指数的遗传度为76%,男、女性分别为33%,74%;腰臀围比值的遗传度为62%,男、女性分别为0.12%,74%。结论在体型指征的相关指标中,BMI和WHR均受遗传因素影响较大。其中,女性的BMI和WHR受遗传因素的影响可能大于环境因素;男性体质指数受环境因素影响大于遗传因素,腰臀围比值则可能不受遗传因素影响。

关 键 词:成人双生子  遗传度  结构方程模型  体型指征
文章编号:1001-0580(2005)04-0413-03
修稿时间:2004年8月9日

Heritability analysis on body size indices of adult twins in Qingdao
WU Weifeng,PANG Zengchang,MA Aiguo.Heritability analysis on body size indices of adult twins in Qingdao[J].Chinese Journal of Public Health,2005,21(4):413-415.
Authors:WU Weifeng  PANG Zengchang  MA Aiguo
Institution:WU Weifeng,PANG Zengchang,MA Aiguo.Department of Nutrition in Medical School of Qingdao University
Abstract:Objective To discuss the extent that inheritance impacts on body size indices,which include body mass index (BMI) and wais-to-hip ratio(WHR).Methods Based on zygosity identification,the heritability of body size indices was studied for 496 pairs of twins,aged on less than 24 years old,who were voluntary to participate in this study.Mx software package was used as the statistical method to build structural equation models.Results The heritability estimated for BMI was76%,which was 33% and 74% for male and female respectively.For WHR,the heritability was 62%,0.12% and 74% respectively for male and female.Conclusion Among the factors of body size,BMI and WHR are both influenced mostly by inheritance.For females,inheritance influnces mostly on BMI and WHR.For males,the inheritable influence is larger than environmental factors on BMI and is little on WHR.
Keywords:adult twins  heritability  structural equation models  body size indices
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