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血清铁锌铜及免疫球蛋白与复发性阿弗他溃疡相关性研究
引用本文:闫雅更,白桦,董凤丽,孙文广,张琳,郭晓微.血清铁锌铜及免疫球蛋白与复发性阿弗他溃疡相关性研究[J].疾病控制杂志,2011,15(12):1024-1025.
作者姓名:闫雅更  白桦  董凤丽  孙文广  张琳  郭晓微
作者单位:哈尔滨医科大学附属第一医院临床营养科,黑龙江哈尔滨,150001
基金项目:哈尔滨医科大学附属第一医院科研基金(2009Y14)
摘    要:目的 探讨血清微量元素铁锌铜及免疫球蛋白与复发性阿弗他溃疡(recurrent aphthous ulcer,RAU)的关系.方法 RAU患者102例作为病例组,选择年龄、性别相匹配的86例健康人群作为对照组,两组分别采集空腹静脉血,用全自动生化分析仪测血清铁、锌、铜含量,用特种蛋白检测仪测血清免疫球蛋白水平,并与正常值比较.结果 病例组血清铁的缺乏率14.71%,高于对照组(5.81%),差异有统计学意义(P=0.049);两组间血清锌、血清铜的缺乏率均没有统计学差异(均有P >0.05).两组间血清免疫球蛋白水平均没有统计学差异.结论 RAU病因复杂,微量元素缺乏、免疫球蛋白异常证据不足,还需进一步做大样本研究.

关 键 词:口炎  口疮性  免疫球蛋白类  病例对照研究

Study on the correlation of recurrent aphthous ulcer with the concentration of serum iron,zinc-copper and immunoglobulin
YANYa-geng , BAI Hua , DONG Feng-li , SUN Wen-guang , ZHANG Lin , GUO Xiao-wei.Study on the correlation of recurrent aphthous ulcer with the concentration of serum iron,zinc-copper and immunoglobulin[J].Chinese Journal of Disease Control and Prevention,2011,15(12):1024-1025.
Authors:YANYa-geng  BAI Hua  DONG Feng-li  SUN Wen-guang  ZHANG Lin  GUO Xiao-wei
Institution:YAN Ya-geng,BAI Hua,DONG Feng-li,SUN Wen-guang,ZHANG Lin,GUO Xiao-wei.Department of Nutrition,the First Affiliated Hospital of Harbin Medical University,Harbin 150001,China
Abstract:Objective To study the relationship of Iron,Zinc-Copper,immunogloblin in serum with recurrent aphthous ulcer(RAU).Methods 102 patients with RAU and 86 healthy controls were recruited.The age and sex were matched in two groups.The concentration of Iron,Zinc,-Copper,immunogloblin were measured in serum by Automatic Biochemistry Analyzer and Special Protein Detector respectively.Results The serum iron of RAU group was more deficient(14.71%) than the control(5.81%),there was significant difference between two g...
Keywords:Stomatitis  aphthous  Immunoglobulins  Case-control studies  
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