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手足口病病例密切接触者和健康人群肠道病毒带毒率调查
引用本文:曾汉日,张永慧,孙立梅,郑焕英,管大伟,邓爱萍,柯昌文,李晖,黎薇.手足口病病例密切接触者和健康人群肠道病毒带毒率调查[J].中国卫生检验杂志,2012(5):1158-1159,1162.
作者姓名:曾汉日  张永慧  孙立梅  郑焕英  管大伟  邓爱萍  柯昌文  李晖  黎薇
作者单位:广东省疾病预防控制中心
基金项目:广东省医学科研项目(C2010016)
摘    要:目的:了解广东省手足口病病例密切接触者和健康人群肠道病毒带毒状况。方法:选取广东省珠三角和非珠三角两个地区手足口病病例密切接触者及健康人群作为调查对象,采集标本进行病原学检测,对结果进行统计分析。结果:密切接触者和健康人群之间EV71(P<0.05)、CoxA16(P<0.01)各自的阳性率差异有统计意义;珠三角和非珠三角两地区密切接触者EV(P<0.05)、CoxA16(P<0.05)以及两地区健康人群EV(P<0.01)各自的阳性率差异有统计意义。结论:广东省手足口病病例密切接触者EV71和Cox-A16感染率高于健康人群;健康人群以携带非EV71非CoxA16肠道病毒为主。

关 键 词:手足口病  密切接触者  健康人群  EV71  CoxA16

Investigation on the carrying rate of enterovirus in healthy population and close contacts of HFMD cases
ZENG Han-ri,ZHANG Yong-hui,SUN Li-mei,ZHENG Huan-ying,GUAN Da-wei,DENG Ai-ping,KE Chang-wen,LI Hui,LI Wei.Investigation on the carrying rate of enterovirus in healthy population and close contacts of HFMD cases[J].Chinses Journal of Health Laboratory Technology,2012(5):1158-1159,1162.
Authors:ZENG Han-ri  ZHANG Yong-hui  SUN Li-mei  ZHENG Huan-ying  GUAN Da-wei  DENG Ai-ping  KE Chang-wen  LI Hui  LI Wei
Institution:(Center for Disease Control and Prevention of Guangdong Province,Guangzhou 510300,China)
Abstract:Objective:To study the carrying rate of enterovirus in healthy population and close contacts of HFMD cases in Guangdong Province.Methods: The samples from healthy population and close contacts of HFMD cases in Guangdong Province(Pearl River Delta region and non-Pearl River Delta region) were collected for identification and the detection data were analyzed by using statistical software.Results: There were significant differences in the positive rates of EV71(P<0.05) and CoxA16(P<0.01) between healthy population and close contacts;The positive rates of EV(P<0.05)and CoxA16(P<0.05) in close contacts in Pearl River Delta region were higher than those in non-Pearl River Delta region,and there was a significant difference in the positive rate of EV(P<0.01) in healthy population between the two regions too.Conclusion: The infection rates of EV71 and CoxA16 in close contacts of HFMD cases were significantly higher than those in healthy population in Guangdong Province;The healthy population mainly carried the enterovirus of non-EV71 and non-CoxA16.
Keywords:Hand-foot-mouth disease  Close contacts  Healthy population  EV71  CoxA16
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