| 百草枯中毒病理机制研究进展 |
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| 引用本文： | 王晔,金波,刘敏,廖志钢.百草枯中毒病理机制研究进展[J].卫生研究,2006,35(3):366-369. |
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| 作者姓名： | 王晔 金波 刘敏 廖志钢 |
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| 作者单位： | 四川大学华西基础医学与法医学院,成都,610041 |
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| 摘 要： | 百草枯是农业生产中广泛使用的一种除草剂,但也有较强的毒性,易致人畜中毒,目前尚无特效解毒剂。目前研究认为其中毒损伤机制主要是通过其强氧化作用,使机体内还原酶及脂质的氧化,或直接或间接损伤DNA,使细胞坏死或凋亡。
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| 关 键 词： | 百草枯 中毒 病理机制 |
| 文章编号： | 1000-8020（2006）03-0366-04 |
| 收稿时间： | 2005-06-15 |
| 修稿时间： | 2005年6月15日 |
Advance of study on pathological mechanism of paraquat poisoning |
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| Wang Ye,Jin Bo,Liu Min,Liao Zhi-gang.Advance of study on pathological mechanism of paraquat poisoning[J].Journal of Hygiene Research,2006,35(3):366-369. |
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| Authors: | Wang Ye Jin Bo Liu Min Liao Zhi-gang |
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| Institution: | West China School of Preclinical and Forensic Medicine, Sichuan University, Chengdu 610041, China |
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| Abstract: | Paraquat which is used widely as a potent herbicide is poisonous, and its pathological mechanism is unclear. Studies show that it is so a strong oxidant that it can oxidate lipid and some enzyme, also, it can damage DNA directly or induce necrosis or apoptosis, which is marked in pulmonary. To offer new directions for treatment and studies on paraquat poisoning, this paper reviewed the foreign studies on mechanism of it. |
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| Keywords: | paraquat poisoning pathological mechanism |
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