| 二硫化碳对大鼠胚胎发育及血清锌和铜含量影响的研究 |
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| 引用本文： | 王玉玲,保毓书.二硫化碳对大鼠胚胎发育及血清锌和铜含量影响的研究[J].卫生研究,1988(6). |
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| 作者姓名： | 王玉玲 保毓书 |
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| 作者单位： | 中国预防医学科学院劳动卫生与职业病研究所，北京医科大学公共卫生学院 |
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| 摘 要： | 本文观察了CS_2对大鼠胚胎发育及血清锌、铜含量的影响。发现胚胎着床前死亡率升高,胎鼠皮下出血、心包淤血及骨骼骨化不金的发生率增高。但无明显的致畸效应。14.1及103.9ng/m~3的CS_2对妊娠大鼠的血清锌、铜含量无明显影响。说明CS_2对大鼠的胚胎毒性与其对妊娠大鼠血清锌、铜含量的影响之间没有关联。
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| 关 键 词： | 二硫化碳 大鼠胚胎发育 血清锌 血清铜 |
A Study on the Embryotoxicity of Carbon Disulfide and its Effect on the Serum Zinc and Copper in Pregnant Rats |
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| Wang yu-ling and Bao yu-shu.A Study on the Embryotoxicity of Carbon Disulfide and its Effect on the Serum Zinc and Copper in Pregnant Rats[J].Journal of Hygiene Research,1988(6). |
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| Authors: | Wang yu-ling and Bao yu-shu |
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| Institution: | Wang yu-ling and Bao yu-shu~* |
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| Abstract: | The embryotoxcty of carbon disulfids (CS_2) and its effect on the serum zinc and copper wers studied when pregnaat rats exposed to CS_2 in concentrations of 14.1mg/m~3 and 103.9mg/m~3. The embryotoxicity mainly manifested as the increasing of pre(?)mplantation mortality and. incidences of petechlal hemorrhage, hemoper(?)cardium and skeletal alternation. But its teratogenic effect was not obvious. The concentrations of CS_2 in 14.1mg/m~3 and 103.9mg/m~3 had no effect on serum zinc and coppsr in pregnant rats. It is suggested that the embryotoxicity of CS_2 is not interrelated to the effect of CS_2 on the serum zinc and copper in pregnant rats. |
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| Keywords: | carbon disnlfide embryo toxicity rats serum zinc and copper |
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